Param P Singh
@param_p_singh
Assistant Professor @UCSF, @UCSFAging studying aging, diapause and evolution using killifish and computational biology.
ID: 2932948094
http://SinghLabUCSF.org 17-12-2014 02:27:00
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Grateful to partner with Jonathan Weissman's Lab on a project led by Richard She and TYLER FAIR exploring the extent and identity of human-specific genetic dependencies sciencedirect.com/science/articl…
Perspective co-authored with Param P Singh out today in Nature Aging, where we outline best practices in "omics" for #aging research. We outline biological and technical considerations key to #reproducible results. rdcu.be/dfGsi
Our perspective with Bérénice A. Benayoun, PhD on best practices for omics experiments in aging research is out in Nature Aging We hope this is useful for the aging community and beyond. nature.com/articles/s4358… UC San Francisco UCSF Bakar Aging Research Institute
Online now! New review in Trends in Cancer on MiT/TFE transcription factors, lysosomes and cancer with Roberto Zoncu. We highlight emerging modes of MiT/TFE regulation and activity in cancer. Free online for 50d at this link: authors.elsevier.com/a/1hLMI8Z12yTu…
Incredibly excited to share our paper on chromatin changes in neural stem cells during aging It revealed defects in cell migration with age! CONGRATS to @robinwyeo and Olivia Zhou! Awesome collaboration with Anshul Kundaje (anshulkundaje@bluesky) and Alex Dunn! 🎉🥂 nature.com/articles/s4358…
Killifish lab manual with a collection of latest protocols, edited by Brunet Lab
A long time ago, Olivier Elemento and I came up with our solution to the gene-set enrichment analysis. We used mutual information to measure the association between gene-set membership and input. After a decade, a talented undergrad spearheaded an update: biorxiv.org/content/10.110…
The goal of science is reproducibility. Newly published stories out in nature, Nature Aging, and Nature Communications today show it's possible for researchers to independently come to the same conclusion, identifying PF4 as cognition enhancing blood factor 🧵1/4
Postdoctoral fellow to study aging and diapause in the African killifish Param P Singh Postdoc position in the Singh Lab at UCSF to study aging, age-related diseases, and diapause using multi-omics in the African killifish. jobrxiv.org/job/singh-lab-… #... jobrxiv.org/job/singh-lab-…
Our lab UC San Francisco and UCSF Bakar Aging Research Institute is looking for #postdocs to study the biology of #aging and #diapause using African killifish and integrative genomic approaches. Please get in touch, and please spread the word!
What Alzheimer noted as fat saccules in glia may have been lipid droplets. They can be induced by Abeta in microglia leading them to release factors that damage neurons. ApoE4 makes things worse rdcu.be/dA6Kh. Congrats Michael Haney Robert Palovics and fantastic team
Stunning talk from Jason Buenrostro at #singlecellgenomicsday, highlighting how to squeeze TF footprinting insights out of scATAC-seq data, and identifying transcription factors that drive HSC aging.
I'm excited to share our study on the evolution and regulation of diapause in killifish, out today Cell! Thank you to all the co-authors and collaborators! 🙏 Brunet Lab Michael Snyder, PhD Chi-Kuo Hu Katharina Papsdorf Jason Miklas @KContrepois, Adam Reeves! cell.com/cell/fulltext/…
Beyond thrilled to share 3 papers on the killifish from our lab and fantastic collaborators!! 🐟🙌 Two on protein aggregates during aging – with Jarosz Lab! cell.com/developmental-… cell.com/cell-reports/f… One on evolution of 'suspended animation'! cell.com/cell/fulltext/…
