Today in Nature Medicine we report that AI can predict 130 diseases from 1 night of sleep🛌 We trained a foundation model (#SleepFM) on 585K hours of sleep recordings from 65K people—brain, heart, muscle & breathing signals combined. AI learns the language of sleep🧵

Each week I’m more and more impressed with what AI can accomplish with scientific content. I fed my book ‘VO2 Max Essentials’ into NotebookLLM and created this infographic that outlines several of the key points from the book.

Your gut isn’t just digesting food… It’s running a biochemical factory that keeps you alive. Most people think the colon is just “where waste goes.” But this illustration shows something more: Your colon is one of the most underrated metabolic organs in the entire body.

Ten thousand steps is good. But… Breaking up sitting time is better. When you sit for hours: • Blood sugar rises • Inflammation rises • Circulation drops • Muscle inefficiency kicks in You can counter this by: Standing up every 45 minutes. Do 10 squats. Walk for two

The role of fermented foods in healthy longevity: A review of potential anti-aging mechanisms ▶️Fermented foods are defined as “foods made through desired microbial growth & enzymatic conversions of food components”. ▶️Fermented foods exhibit anti-aging potential through both

You are not ageing faster because life is stressful. You are ageing faster because it is too comfortable. This sounds wrong. But biologically, it makes sense. Human physiology evolved expecting short bursts of stress followed by recovery. Movement. Temperature extremes.

Mitochondria are not just power plants. They are decision-makers. They regulate inflammation, aging, and disease. A quick breakdown: 🔵 Energy signaling, not just energy production Mitochondria don’t just make energy. They decide how energy is produced, where it’s used, and

Coffee already modulates inflammatory pathways via its polyphenols, particularly chlorogenic acid. You can increase the anti-inflammatory benefits with these: • Protein (soy or dairy)→ stronger polyphenol binding • Cinnamon → reduces inflammatory markers • Cocoa → lower

Green tea contains many bioactive compounds that target all the hallmarks of aging: - genomic instability - telomere attrition - epigenetic alterations - loss of proteostasis - impaired autophagy - deregulated nutrient sensing - mitochondrial dysfunction - cellular senescence -

Here’s what happens to your body after just 30 seconds of performing an all-out sprint. Most people think sprinting is just another form of cardio, something you do to burn a few extra calories. But what actually happens inside your body during those 30 seconds is

Central role of skeletal muscle ageing in the pathogenesis of sarcopenia Potential pathways👇 ✅insufficient myokine signalling (IL-6, 7, 15) ✅altered immune factors (pro-inflammatory profile) ✅impaired immune cell function ✅altered body composition sciencedirect.com/science/articl…

Stop treating sleep like a luxury. Let me explain: No amount of green juice or gym time can undo the damage of chronic sleep debt. I’ve never met anyone who glowed from 5 hours a night and a gratitude journal. No stress relief hack can compensate for a good night's sleep.

Article Summary: How to fix your entire life in 1 day

How Exercise Talks to Your Body & Brain 🏋️‍♂️🧠💪 Exercise isn’t just moving muscles...it turns them into endocrine powerhouses that signal your brain, bones, and metabolism. Here’s what really happens: 1. Lactate – the fuel & brain booster High-intensity lifting or cardio →

80+ and Faster Than Your Excuses: The 50 km Aging Limit Just Got Shattered 1) The feat - 81-year-old male set the 80+ world record in the 50 km in 2025 - Time: 4:47:39 - Avg speed: 10.5 km/h (about 5:44 per km) 2) The headline physiology - VO2max: 52.8 mL/kg/min (treadmill) -