New content online: Metformin: update on mechanisms of action and repurposing potential dlvr.it/SnQW0l

Excited to share my PhD work investigating how nitrate impacts metabolism in diet-induced obesity, now out on BioRxiv as a preprint! 👇 Many thanks to Andrew Murray, Jules Griffin, Martin Feelisch (not on Twitter) and everyone who worked on this project

Not that we ever need excuse for cakes - but we recently did so when advised that we are successful in a MRFF research grant application with old friends Betty Raman and Dr Thanh Ha Nguyen. Grateful to all who helped and looking forward to do the work! Heart Foundation Diabetes SA

UKPDS - keeps giving! Benefits sustained 24 years after end of trial Early intensive glycaemic control confers a near-lifelong reduced risk of death and myocardial infarction and microvascular complications. thelancet.com/journals/lance… Congratulation Amanda I Adler et al 👏

A new review Nature Metabolism The intricate communication between the brain and the periphery, highlighting the effect of #obesity induced inflammation on brain function. nature.com/articles/s4225…

A global initiative to deliver precision health in diabetes. Comment from William Cefalu NIDDK and colleagues nature.com/articles/s4159…

A Science Immunology Review contextualizes advances in CAR T cell #cancer immunotherapy, summarizing studies that explore the impact of metabolic stress on this treatment’s efficacy in the tumor microenvironment. Learn more: scim.ag/8o1 #ScienceMagArchives

A new study in Science Immunology suggests that moderate #fevers impair electron transport chain complex 1 function and drive mitochondrial damage in T helper 1 cells. 📄: scim.ag/8oc

A novel immunotherapy strategy using in vivo generation of engineered CAR T cells can reduce fibrosis and restore cardiac function in a mouse model of heart failure, a 2022 Science study reports. Learn more on #WorldHeartDay: scim.ag/4u

Congratulations to our PhD student Get Z Negera for winning the best oral presentation in the category of senior laboratory research at Basil Hetzel Institute research expo! Well done! Uni of Adelaide Diabetes SA Heart Foundation

Women are still under-represented in medical research. Here’s where the gender gap is most pronounced time.com/7171341/gender…

Do you have a great research idea that could address an unmet need in cardiovascular health and care? We want to hear from you! Take 10 minutes to complete our survey and help shape our future research priorities. bit.ly/3YB8BfN

Importance of the liver's vagus nerve for regulating circadian rhythm of food intake science.org/doi/10.1126/sc… @LaurenNWoodie science.org/doi/10.1126/sc… Noelia Martinez-Sanchez david ray Science Magazine Science Visuals liver-brain axis for potential anti-obesity target

SA has the highest proportion of elderly on mainland Australia, and 🫀 disease is the single leading cause of death here. We thank Mark Butler MP for sharing his views on the role of government in managing 🫀 disease in an ageing population #sacvrnshowcase2024

Prof Sophia Zoungas John McNeil Monash University Prash Sanders Chief Scientist for South Australia SAHMRI Uni of Adelaide Wendy Keech Health Translation SA with Peter Psaltis and Renuka Visvanathan Basil Hetzel Institute

Discovery research generates new knowledge for cures or measures for 🫀disease. Exciting to hear about research spanning from pre-conception to the elderly Claire Roberts FlindersHMRI Sophie Wiszniak UniSA Peter Zalewski & John Horowirz Basil Hetzel Institute #sacvrnshowcase2024

Discussing the reciprocal interaction between #Epigenetics and #metabolism by focusing on histone #acetylation and its capacity to act as acetate reservoir. Many thanks to Evelina charidemou Trends in Biochemical Sciences editorial team and anonymous reviewers cell.com/trends/biochem…

Thanks for the invitation to join the panel discussion virtually. It’s great to hear about other speakers’ experience. I hope our discussions sparked joy and that someone found something useful ❤️ Basil Hetzel Institute Uni of Adelaide SA CVRN