Adipose tissue macrophage infiltration and hepatocyte stress increase GDF-15 throughout development of #obesity to #MASH Nature Communications nature.com/articles/s4146…

Myosteatosis predicts bariatric surgery response: A longitudinal study in patients with morbid #obesity Endocrine Society Journals academic.oup.com/jcem/advance-a…

Lipid-associated macrophages’ promotion of #fibrosis resolution during #MASH regression requires TREM2 PNASNews pnas.org/doi/10.1073/pn…

Hic-5 antisense oligonucleotide inhibits advanced hepatic fibrosis and steatosis in vivo #MASLD JHEP Reports jhep-reports.eu/article/S2589-…

Targeting the liver clock improves fibrosis by restoring TGF-β signaling Journal of Hepatology journal-of-hepatology.eu/article/S0168-…

Glucagon promotes increased hepatic mitochondrial oxidation and pyruvate carboxylase flux in humans with fatty liver disease #MASLD Cell Metabolism cell.com/cell-metabolis…

PCPE-1, a brown adipose tissue-derived cytokine, promotes obesity-induced liver fibrosis #MASLD #MASH The EMBO Journal embopress.org/doi/full/10.10…

Aldehydes alter TGF-β signaling and induce #obesity and #cancer Cell Reports cell.com/cell-reports/f…

Sex- and age-associated factors drive the pathophysiology of #MASLD Hepatology Communications journals.lww.com/hepcomm/fullte…

Spatial single-cell isotope tracing reveals heterogeneity of de novo fatty acid synthesis in cancer Nature Metabolism nature.com/articles/s4225…

SGLT2 inhibitor promotes ketogenesis to improve #MASH by suppressing CD8+ T cell activation Cell Metabolism cell.com/cell-metabolis…

Four-year fully funded #PhD position available in our #hepatology lab at Pharmacology Valencia Universitat València 📢 Join our group to investigate new therapeutic options to prevent and reverse #liver #fibrosis More info: uv.es/uvweb/servicio…

Postprandial metabolomics analysis reveals disordered serotonin metabolism in post-bariatric hypoglycemia #obesity Journal of Clinical Investigation jci.org/articles/view/…

Adipocyte inflammation is the primary driver of hepatic insulin resistance in a human iPSC-based microphysiological system #MASLD #diabetes Nature Communications nature.com/articles/s4146…

Hepatic miR-149-5p upregulation fosters steatosis, inflammation and fibrosis development in mice and in human liver organoids #MASLD JHEP Reports jhep-reports.eu/article/S2589-…

HIF-2α drives hepatic Kupffer cell death and proinflammatory recruited macrophage activation in #MASH Science Translational Medicine science.org/doi/full/10.11…

Therapeutic siRNA targeting PLIN2 ameliorates steatosis, inflammation, and fibrosis in #MASLD models Journal of Lipid Research jlr.org/article/S0022-…

Disruption of HSD17B12 in mouse hepatocytes leads to reduced body weight and defect in the lipid droplet expansion associated with microvesicular steatosis FASEB faseb.onlinelibrary.wiley.com/doi/full/10.10…

IF1 is a cold-regulated switch of ATP synthase hydrolytic activity to support thermogenesis in brown fat The EMBO Journal embopress.org/doi/full/10.10…

Looking for PhD students/postdocs for my newly opened lab at the Institute of Human Biology of #Roche in Basel. We work on human lung, liver and gut #organoids. Send email + CV + motivation letter to [email protected] with header #IHB institutehumanbiology.com