Paul G Thomas
@PGTimmune
Department of Host-Microbe Interactions, St. Jude Children's Research Hospital
ID:4864988228
https://www.stjude.org/directory/t/paul-thomas.html 05-02-2016 15:37:40
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FOXO1 drives memory programming, stemness, and metabolic programming in CAR T cells nature Mackall Lab Evan Weber Junyun Lai A/Prof Paul Beavis DarcyLab Peter Mac Cancer Centre
nature.com/articles/s4158…
nature.com/articles/s4158…
#MysterySolved ! Krönke &co show nature that glucocorticoids are anti-inflammatory not in a transcriptional manner (🤯), but by boosting the Krebs cycle in macrophages, driving excessive #itaconate that interferes with pro-inflammatory cytokine induction! Doi.org/10.1038/s41586…
I am very excited to see this in print!
New work from our lab defines an interferon-induced memory B cell subset during chronic viral infection.
An awesome effort by Lucy Cooper Lucy Cooper & supported by our generous lab members & collaborators
Monash Biomedicine Discovery Institute Immunity
The difference in 10x Genomics' Cell Ranger's default between version 6 and 7 is discussed in this thread, but it's such a big deal that it's worth its own thread.
tl;dr: in v7 Cell Ranger changed how it produces the gene count matrix leading to a huge difference in results. 1/
Congratulations to multiple cancer center members including Dr. Evan Glazer for this groundbreaking effort in the rare disease fibrolamellar carcinoma and our collaboration with St. Jude.
The University of Tennessee Health Science Center UTHSC Research UTHSC Center for Cancer Research St. Jude
cell.com/cell-reports-m…
Richard Webby, PhD, Virologist at St. Jude, is researching the spread of the H5N1 bird flu virus as it aggressively spreads in non-human mammals. Find out what is raising the alarm in Reuters Science News. ow.ly/tn5y50QUH7i