Trem2 agonist reprograms foamy macrophages to promote atherosclerotic plaque stability. Online today, ahead of print. ahajournals.org/doi/10.1161/AT…

One week countdown to #VascularDiscovery24 is on! New to the conference? Wanting to make new connections? Join the ATVB Early Career Committee during Poster Session 3, where we will designate a spot to network, socialize, and mingle with new peers! We look forward to meeting you there 👋

Join us tomorrow at noon as CFI presents the 61st Annual J.S. and H.R Blumenthal Memorial Lectureship Series featuring Dr. Kate Fitzgerald (Kate Fitzgerald). Add to calendar: z.umn.edu/9ihl

I'm happy to share that out paper on Phantasus, a web-application for visual and interactive gene expression analysis, got out in eLife - the journal elifesciences.org/articles/85722 Here, I'm using it to analyze a random GEO dataset, including basic QC to filter outliers, in under 100 seconds! 1/n

Jumpstart your morning w ATVB Early Career Committee as they kick off #VascularDiscovery24 w two sessions (both 7am Salon A1), tailored toward early career members. Thursday’s session will host roundtable discussion while Friday’s will ft an amazing panel discussion! Don’t miss these!! 📚

Hannah and I had a great time at ATVB Council Vascular Discovery in Chicago! Thanks for all the feedback on our work; see you at AHA Sessions in Nov!

A Call from the ATVB Early Career Committee : Do not miss the opportunity to present your research and compete for the Elaine W. Raines Early Career Investigator Award, sponsored by ATVB Council, Deadline June 10th 2024. To submit: professional.heart.org/en/professiona…

Be center stage with our most prominent ATVB early career members by applying for the Elaine Raines Award Competition at #AHA24! I’ve loved watching the previous years’ award winners and finalists grow within ATVB, & look forward to seeing the next group of leaders shine 🤩

Happy to share our newest Trem2 Foamy Macrophage study that is available - open access - at ATVB! This was a great team effort and an exciting area of continued research!

Our latest JCI Insight paper addresses the formation of Trem2+ Lipid Associated Macrophages (LAMs) in the adrenal gland after acute or chronic stress responses: Adrenal gland macrophages regulate glucocorticoid production through Trem2 and TGFβ UMN Integrative Biology & Physiology insight.jci.org/articles/view/…

Lipid-associated macrophages reshape BAT cell identity in obesity: Cell Reports 🔥thanks to my colleague and friend Daniele Lettieri Barbato for leading this groundbreaking research on BAT macrophages! It was a pleasure to collaborate on this achievement. cell.com/cell-reports/f…

Final version is online at JCI insight : Our study examined the response of adrenal gland macrophages following acute or chronic stress responses, finding a role for Trem2+ Lipid Associated Macrophages in regulating stress hormone production. UMN Integrative Biology & Physiology insight.jci.org/articles/view/…

Williams lab was well represented at UMN CardioPalooza yesterday. Front row seats for the symposium and posters from Hannah, Yingzheng, and undergrad Sia! UMN Integrative Biology & Physiology

Summer lab outing to the lake 🔬🥼🧪, of course it rained 🌧️☔️⛈️

Spend the last bit of summer soaking up the sun with Hearty by visiting a lake! Many lakes provide a great place to walk, swim, and relax. Don't forget the sunscreen! ☀️ ❤️

Excited to see our publication in press Circulation complete with a fantastic editorial by Constance Delwarde Aikawa-Aikawa Laboratories . Our study was featured in this week’s Circulation on the Run podcast. Congratulations Sohel Shamsuzzaman, Becca Deaton and co-authors! ahajournals.org/doi/full/10.11…

Join us for a fun conversation about mentoring! I will be talking with 3 amazing women that I have had the honor of mentoring about the mentor/mentee relationship. Be there!! Dr. Filiz Korkmaz

Congratulations Ziad Mallat for making it from bench to bedside!!! IVORY results released by Rouchelle Sriranjan Rothwell at #ESCCongress Low dose IL2 safely reduce arterial inflammation after ASC VPD Heart & Lung Research Institute CambridgeCardio Cambridge Department of Medicine British Heart Foundation

Saturday at #AIC2024 will focus on innate immunity and features talks by Drs. Steve Wagonner Waggoner Lab, Thiru Kanneganti Thirumala-Devi Kanneganti, Mark Headley Mark Headley Lab and Stephania Cormier Stephania Cormier

Check our paper in nature nature.com/articles/s4158… This is a huge collaborative work combining great basic and clinical science, with important implications for the prevention of atherosclerotic cardiovascular disease. Thanks to all our collaborators and funders!