It’s a tough life to be a UMass Chan Program in Innate Immunity trainee - glad you enjoyed #toll2024

#WeekendRead ! #EveryCellIsAnImmuneCell ! Marshak-Rothstein, Kate Fitzgerald, &co show Cell Reports that a STING gain-of-function mutation expressed exclusively in #EndothelialCells is sufficient to drive the immune cell accrual in the #lung typical of SAVI! t.ly/nHtgB

It has been an immense privilege and honor to review with John MacMicking and Carl Nathan in Science Magazine the past 40 years of IFN-gamma research, and reflect on its neglected and potential role as a medicine

science.org/doi/epdf/10.11…

Congratulations Peterson Lab - well deserved

In summary, we find that endothelial intrinsic STING activation initiates pulmonary immune infiltration. Thus, inhibition of endothelial STING activation may mitigate lung inflammatory disease in patients with SAVI and potentially other types of ILD (7/7)

Great thread summary of this exciting work ImmunoKevin Kristy Chiang

Josefowicz Lab Liraz Galla UT Southwestern Medical Center discusses the mechanism of lcRNA in colonic homeostasis and inflammatory bowel disease in collaboration with Kate Fitzgerald

UMass Chan Medical School & MITRE are creating the Health AI Assurance Laboratory, the first program in Mass. to ensure #AI technology in health care is safe & effective for everyone using it: brnw.ch/21wIHDN

MITRE MA EOED MassTech Collaborative David McManus UMass Chan – Community & Government Relations

UMass Chan and MITRE launched the Health Al Assurance Laboratory with support from a $555,000 MassTech grant to advance artificial intelligence in the public interest. MITRE MA EOED MassTech Collaborative David McManus UMass Chan – Community & Government Relations

Very nice piece in Current Biology on my colleague in UMass Chan Department of Neurobiology UMass Chan Medical School Ev Yemini. We are so lucky to have him in our department. A star for sure!

We are thrilled to feature Dr. Rahul Sood as our April Chair’s Spotlight! I recently had the pleasure of speaking with Dr. Sood about his work in lung cancer screening, #roboticbroncoscopy , & the innovative RODAT pathway utilized to assess lung nodules. Learn more below!

Congratulations Priya Devarajan !!

Can we harness #immunometabolism to promote atherosclerosis regression? Check out our findings in PNAS showing the role of the IRG1-itaconate axis in atherosclerosis Yannick Cyr Fazli Bozal. Thanks to our collaborators GiannarelliLab NYU CVRC PNASNews 🧵pnas.org/doi/10.1073/pn…

Congratulations SchaferLabUMassChan UMass Chan Department of Neurobiology

Our preprint on human in-vitro neuroinflammation model for Alzheimer's disease. This will allow us to test the molecular effects of various viruses or pathogens on readouts associated with AD.

biorxiv.org/content/10.110…

Congrats 🎈🍾🎉 Amer Lab

Congratulations to Skylar Wright & Priya @kailasanvanaja on revealing how the coincidental sensing of a bacterial toxin and a PAMP determines macrophage cell fate!! Happy to have played a small part in this paper!

It was a great experience working with VI4Research artist in residence ! Kristy Chiang Mingqi Dong Shrutika Mintri - Thanks ellyce and the other artists we worked with 🙏

We are still on the lookout for another talented postdoc to join our lab! Apply now or share with your network 👇🏻

Congratulations Ruslan Medzhitov