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Looking forward to chatting about the best cytokine (IFNg) and parasite (cryptosporidium) combination today at 2:30! Come see me at poster 503 at #AAI2023

“…And when our work is done, Our course on earth is run, May it be said, ‘Well done Be thou at peace.’ E'er may that line of gray Increase from day to day Live, serve, and die, we pray, West Point, for thee.” - West Point Alma Mater

Know lots of Penn Engineering alums (@Lola_UMich Ilya Levental) that will be sad to hear this: inquirer.com/news/magic-car…

Want to learn more about CD8+ T cell responses during infection in the intestine? Check out our preprint! biorxiv.org/content/10.110…

Huzzah!

Kandice Levental and Ilya Levental to Receive 2024 Avanti Award in Lipids ow.ly/npZi50PLIKI

Who likes enteric pathogens and the DC and CD4 T cells that control them? Ian Cohn and Boris Striepen find a role for DC1 in supporting CD4 responses to Crypto. Terrific use of transgenic parasites to track priming, effector responses and parasite control. biorxiv.org/content/10.110…

So conflicted…not really.

⚡️New preprint out! #Immunology #biophysics 1/ We show hidden functional immune cell states based on collective membrane properties, which are not directly visible via cell surface markers. biorxiv.org/content/10.110…

Why do activated T/B cells wait to divide? Why is there heterogeneity in their daughter cell responses? How do we find peace in these troubled times? Check the Bailis Lab’s FIRST PAPER (🎉) for insight into 2 of these 3 questions! science.org/doi/10.1126/sc…

In its 184 year history Journal of Experimental Medicine has not published a manuscript on Cryptosporidium. Today, an injustice righted with Ian Cohn and Boris Striepen using transgenic parasites to understand how cDC1s regulate T cell–mediated resistance to Cryptosporidium rupress.org/jem/article-ab…

New record for the lab (and not a good one). Revision of latest manuscript contains 79 new figure panels to address reviewers’ questions. To quote Hidde Ploegh: End the tyranny of reviewer experiments!

Read our new paper: Cryptosporidium impacts epithelial turnover and is resistant to induced death of the host cell by Bethan Wallbank out today in mBio. Great team effort with Ryan Pardy ChrisHunter Igor Brodsky journals.asm.org/doi/10.1128/mb… Infected = not apoptotic:

Check out our new paper for a window into Cryptosporidium's life in the gut #cryptosporidium #intestine #MicroscopyMonday

Hey Jonathan Kagan who likes cytokines and mRNA vaccines? Emily Aunins anthonyphan with Mohamad-Gabriel Alameh David Christian, Ph.D. Ross Kedl The Drew Weissman Lab explore how IL-12 mRNA can be used to diversify and improve mRNA vaccine induced CD8 T cell responses - takes a village biorxiv.org/content/10.110…

Preview of some great Global Parasitology Seminars to look forward to this coming semester! Trends in Parasitology British Society for Parasitology Aust Soc for Para parasitesrule ASP-Parasitologists LabEx ParaFrap Penn BGS Women In Malaria Penn Vet Bloodsucking Parasites PEERs in Parasitology (PiP)

Delighted to have my image on the cover of mBio Isn't the #intestine pretty?! Want to see more? Check out our publication that goes with it! Boris Striepen ChrisHunter journals.asm.org/doi/10.1128/mb…

It still hasn't sunk in that I was at the "old folks" table for dinner...

Kevin Wood was a wonderful human being and he is gone way to soon, like a shooting star. I will miss him. Support Future Biophysicists in Kevin's Memory gofund.me/b8bff582

.Ian Cohn Boris Striepen ChrisHunter et al. show that intestinal cDC1s have distinct roles in shaping CD4+ T cell responses to #Cryptosporidium. hubs.la/Q02TJsqr0 📘 In our #Cytokines collection: hubs.la/Q02TJtq20 #cytokines2024