
Chiarle lab
@chiarlelab
Official account of Roberto Chiarle's laboratory @BostonChildrens and @unito
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http://www.chiarlelab.com 08-02-2022 14:31:10
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Nice comment about our recently published paper in @BloodJournal from Karaca-Ataby et al.Elif Karaca Atabay Thanks to Dr. Ryan Wilcox for highlighting our work.


Our work on LINE-1 insertions at CRISPR editing sites is already out! Congratulations to Jianli Tao (Jianli Tao) and Qi Wang (Qi) Chiarle lab. Many thanks to our collaborators from Kathleen Helen Burns to help to make it possible.

A caution on CRISPR in Nature Communications, and the suggestion that base editing and prime editing may be safer from Jianli Tao, Roberto Chiarle, et al. ms.spr.ly/6017b40J9 #mobileelements #jumpinggenes


It is such an honor for us to partner with ALK Cancer Research & @ALKLungCancer to fund research most meaningful to the ALK community. Thank you, Mark Awad, I.DagogoJackMD, Chiarle lab, Dr. Raphael Nemenoff, Dr. John Iafrate, and Liron Bar-Peled for your commitment to research #LCSM


Many others contributed, including many current and former members of my lab, especially Isidro Cortes-Ciriano. Taek from the Roberto Chiarle's lab (Chiarle lab) performed the experiments, my illustrious collaborators Steve Elledge and David Pellman provided insightful comments.

Check out our paper on Science Translational Medicine that deciphers how to overcome ALK TKIs resistance in ALK+ lymphoma by targeting the CCR7-PI3Kgamma pathway. Congrats to all the talented scientists that helped the work! It's on the cover! Boston Children's Università di Torino science.org/toc/stm/15/702


Thanks a lot @CICancer_com for hosting the first RAS Initiative Europe event #TargetingRAS, we enjoyed three days of amazing science! KRASKickers @FredNatLab #KRAS

Fantastic collaboration with Danilo Maddalo and the Genentech team for our review on SHP2 just out Cancer Discovery doi.org/10.1158/2159-8…

Very exciting opportunity to join the faculty Brigham and Women's Pathology : bwh pathology professsor opening - Google Search google.com/search?q=bwh+p…

Our latest publication online now! rdcu.be/dSvhN Nature Communications Amazing team work Santamaria’s Lab Marie-Julie Nokin Biagio Ricciuti, MD PhD Mark Awad Ernest Nadal Cereda Lab

These experiments reveal the full extent of DNA damage caused by L1 expression. The retroelement that built our genome wreaks havoc, too. Powerful implications for cancer biology. Beautiful collaboration with Alice Lee’s and CZ Zhang’s labs. Dana-Farber

Not easy to encompass the growing importance of #ALK in cancers and the progress in treating ALK+ tumors, but this Review might help Chiarle lab Nature Reviews Cancer Boston Children's Università di Torino bit.ly/3XV09bO