The August issue of Cell Research is now available! Discover the latest breakthroughs with 5 research highlights, 3 in-depth articles, and 3 insightful letters to the editor. Stay ahead of the curve by accessing the issue here 👉 nature.com/cr/volumes/34/… #cells #cellresearch #CR

New study by Miao et al. shows how SMYD5-driven RPL40 methylation powers ribosome elongation, linking translation output to hepatocarcinoma growth. SMYD5 emerges as a promising #cancer therapy target! Discover more: nature.com/articles/s4142… #CancerResearch #Ribosome #SMYD5

🔬 New research by Li et al. reveals the 3.6Å resolution cryo-EM structure of H5-bound chromatin fiber! Discover how this detailed view sheds light on chromatin folding and nucleosomal arrays. 👇 nature.com/articles/s4142… #ChromatinStructure #CryoEM #Research

🔬 New research shows that heterochiral protein–protein interactions can be designed from scratch! 🧬 This could unlock mirror-image proteins as new therapies! Check out the full article: nature.com/articles/s4142… #Biomedicine #ProteinDesign #Therapeutics #NewResearch #ScienceNews

Interesting findings from Cancer Cell on T cell clonal dynamics in melanoma treatment below! Thank you for sharing the research as we continue to advance our understanding of molecular and cell biology as a community. #CancerResearch #Immunotherapy #CellResearch

Check out this new review in Nature Reviews Endocrinology on the latest advances in cellular therapeutics for type 1 diabetes. Thrilled to have contributed alongside an incredible team. #DiabetesResearch #CellTherapy #RegenerativeMedicine Read more here: nature.com/articles/s4157…

Review Spotlight! Check out this excellent research into extracellular matrix (ECM) from Nature Reviews Molecular Cell Biology. Naba Lab @ UIC discusses structure, assembly, and new therapeutic strategies for ECM-related diseases. 💡🔬

Beautiful work from Chia-Hsueh Lee, just out in Cell Research #CryoEM structures of human URAT1 provide insights into urate recognition, transport mechanism, and MOA of anti-gout drugs. #OpenAccess nature.com/articles/s4142…

Our work on human urate transporter is out Cell Research. Y. Dai single-handedly drove this project, which revealed the transport and drug mechanism of URAT1. We are grateful for the tremendous support from Structural Biology at St. Jude Children's Hospital nature.com/articles/s4142…

The September issue of Cell Research is now live! 🌟 Explore the latest scientific advances with 6 cutting-edge research highlights, 1 in-depth review article, 2 articles, 2 thought-provoking letters to the editor and 1 correction. ⛰️ This issue includes breakthrough

Assessing clonal changes in T cells over time following immunotherapy is a breeze with Cyclone dlvr.it/TDCj1J

RESEARCH | 🧬 ERVH48-1, once a "genomic relic," is now driving advancements in human urine cell reprogramming! 🌟 Learn how this boosts iPSC creation and its potential in regenerative medicine. #StemCells #Reprogramming #SciComm More at: cellregeneration.springeropen.com/articles/10.11…

Human URAT1 transports urate and is a target for gout treatment. The Lee lab @stjuderesearch presents 10 cryoEM structures of URAT1 with urate, pyrazinoate, and 3 anti-gout drugs, providing mechanistic insights into urate recognition, transport cycle, and inhibition by drugs.

A new study reveals that TMS5 acts as a tRNA 2’,3'-cyclic phosphatase to promote mature tRNA recycling, which safeguards rice male fertility under high temperatures.🌾 Full study: nature.com/articles/s4142… #RiceBreeding #GeneticResearch #cellresearch #CR #cells #cellbiology

Check out this excellent research!🧬 #cells #cellresearch #cellbiology

Transport mechanism and structural pharmacology of human urate transporter URAT1. Cell Research. Check the #cryoEM #structure of this #membrane #protein in the UniTmp database: pdbtm.unitmp.org/entry/9b1f nature.com/articles/s4142…

#Tuberculosis bacteria release tuberculosinyladenosine to help them survive in human #macrophages. This study identifies >100 such #terpene #nucleoside metabolites, revealing how #TB's ancestors acquired the genes to make these lipids #PLOSBiology plos.io/4gIfmol

Thank you, Daniel J Drucker, for sharing this important research! Your high-throughput analysis reveals how protein mislocalization, driven by missense variants affecting stability and membrane insertion, plays a key role in disease-causing mechanisms. A fascinating step forward

We know about #serotonergic signaling in neurons, but what does it do in #GlialCells? This study shows that glial serotonergic signaling is important for experience-dependent #synapse elimination & targeting during #Drosophila development #PLOSBiology plos.io/3zJnDrG