Closing remarks by M. Madan Babu! Thanks everyone for participating in our symposium and for sharing such exciting science. Let's keep the conversation going at the reception!!

Great opportunity in our department: we are looking for a Director for the Cryo-EM Center. The Center is expanding and acquiring cryo-ET/CLEM capabilities, so this is a time of growth and much excitement! Come join our vibrant community at St. Jude! talent.stjude.org/research/jobs/…

Another gem from Chia-Hsueh Lee out nature offers mechanistic insights into human VMAT2 — transporter that packs monoamine neurotransmitters into vesicles — including on MOA of inhibitors tetrabenazine and reserpine and transport of substrate serotonine. nature.com/articles/s4158…

Our TanjaMittag is among the St. Jude scientists on the 2023 Highly Cited Researchers list, compiled by the ISI Clarivate. Congrats Tanja! stjude.org/media-resource…

A #GPCR milestone from M. Madan Babu & Franziska Heydenreich, with Kobilka @stanford Michel Bouvier. Integrating pharmacological and structural data on beta2AR reveals the allosteric network that translates and decodes adrenaline binding into signaling response. science.org/doi/10.1126/sc…

From SunLab, Noma, Martin Turk & Dario Alessi's team MRC PPU, #cryoEM structures of LRRK2–Rab29, including tetrameric assembly with central protomers in sought-after kinase-active conformation — implications for #Parkinsons disease therapeutics science.org/doi/10.1126/sc…

An exciting Collaborative on #GPCR, led by Scott C Blanchard, with a multidisciplinary dream team: M. Madan Babu, @LabSkiniotis, @AliceYTing@JavitchLaband Robert Lefkowitz Duke University School of Medicine

The St. Jude Cryo-EM Center empowers researchers with state-of-the-art tech to visualize genomes in unprecedented detail. Liz Kellogg ❄️🔬, PhD, and her team are now utilizing a “cold FEG” microscope to understand molecular processes for groundbreaking translational studies.

Exciting work from Chia-Hsueh Lee with Matthew Freeman, prefers @mjafreeman.bsky.social out in Molecular Cell reveals the multilayered roles of pseudoprotease iRhom2 in the maturation and regulation of #sheddase ADAM17. #cryoEM #openaccess cell.com/molecular-cell…

Out today in Nature Physics, exciting work from TanjaMittag in collaboration with Rohit V. Pappu and Priya R. Banerjee reveals how amino acid sequence determines the viscoelastic properties and physical aging of biomolecular condensates. nature.com/articles/s4156…