Great afternoon with Piers Portobello Radio , Berta & Lucy, chatting about the importance of sleep and the role it plays in mood regulation & dementia for our upcoming exhibit at Imperial College London UK Dementia Research Institute Great Exhibition Road Festival (15-16/6). Thanks for having us 🙌🏼

New publication alert!📢In the latest work from our group 👇 we've shown that microglia has the highest senescence burden in Alzheimer's disease which positively correlates with beta-amyloid load. Check it out here: link.springer.com/article/10.100…

Super thrilled to be working with brilliant collaborators Dervis Salih and Alexi Nott 🏳️‍🌈 to study gene regulation in oligodendrocytes for our new key questions grant 🥳🥰

Our paper is finally out (my first published first author)! In a tau model, we saw changes in signal encoding in vivo in tandem with synapse and structure alterations. A full summary in the qt below or go read the paper if you’re interested! academic.oup.com/braincomms/art…

The brain’s ability to rid itself of toxins may be reduced during sleep, new UK DRI research reveals🧠💤 Prof Bill Wisden (UK DRI at Imperial) & Prof Nick Franks (Imperial Sciences) found surprising evidence to counter a popular theory as to why we sleep👉buff.ly/3ygEb9j

Happy to share our paper, out this week in Cell Reports. We show that a neuron can act as a frequency mixer, and describe a new method for detecting higher-order frequency mixing interactions in brain activity. Always a pleasure to work with Robert Peach

Calling all budding computational biologist or ECRs who wants to build a career in bioinformatics and computational biology to attend this exciting session of our seminar series.

Please RT🗣️ I have a fully funded #postdoc position (see flyer) as well as a #ResearchAssistant position! If you are interested in #neurodevelopment, somatic #mosaicism and cell #lineages, please consider applying 🧠🧬 And feel free to contact me if you want to know more!!

Research from The University of Sheffield & the UK DRI at Cambridge reveals new insight into how a protein known as apolipoprotein E (APOE) interacts with amyloid-beta, and how this interaction affects the likelihood of developing Alzheimer's👉buff.ly/3VPeCW7

I haven’t advertised my poster yet but I’ll be presenting at #FENS2024 on Friday 2-5:30pm, presenting work from our preprint biorxiv.org/content/10.110… showing characterisation of our human brain slice cultures and the impact of amyloid-b manipulation in these. Come chat! 🧠✌🏽

New research from our group challenges the belief that neurons are a primary source of pathogenic Abeta in #Alzheimer’s. We show oligodendrocytes also produce Abeta, and suppressing oligo Abeta in mice rescues early neuronal dysfunction, suggesting a new therapeutic strategy.

Now at #FENS2024 Dr Soraya M from Claire Durrant lab with her awesome data modelling Alzheimer’s in organotypic human brain slices

I have an exciting PhD position available to join my lab starting this October at the UK Dementia Research Institute . If you are interested in understanding how microglia contribute to Parkinson's disease and want to study cellular interactions using different methods, apply! findaphd.com/phds/project/t…

Today in PLOS Biology, we reveal that in #Alzheimers, not only neurons but also oligodendrocytes produce #Abeta. Targeting #Abeta production in oligodendrocytes alone can rescue early neuronal dysfunction. Read the paper here: journals.plos.org/plosbiology/ar…

We have been awarded Alzheimer's Association funding to study the epigenome of the vasculature in dementia using single nuclei approaches🧠. We are looking for a motivated postdoc to join us UK Dementia Research Institute & Imperial Department of Brain Sciences. Post closes Sept 25th & email me any questions. lnkd.in/gmqAFpUr

A warm welcome back to all ECRs, another exciting academic year is starting 👩‍🎓🧑‍🎓✨ We are back for another year of seminars, workshops and socials🍕✍️👩‍💼🥪 We will kick-start our new 2024-2025 season of the Future Leader seminar series with a talk from Dr AnnaKMallach

We're delighted to announce 3 new UK DRI Emerging Leaders: Maura Malpetti, AnnaKMallach, & Valeria Jaramillo! 🎉 🙌 👏 The initiative supports exceptional ECRs on their journey to setting up an independent lab. Find out more about our new Emerging Leaders👉buff.ly/47lcA4a

Really enjoyed showcasing ultrasound’s potential as a therapeutic tool against Alzheimer’s disease at this year’s ARUK Science Day at the The Royal Society #FocusedUltrasound Bioengineering Imperial College London UK Dementia Research Institute

Interested in psychedelic research?!? The LGBTQ+ Allies network Imperial Department of Brain Sciences is hosting a special symposium featuring david erritzoe Tommaso Barba Joanna Vamvakopoulou from the Imperial Medicine Centre for Psychedelic Research and Gary Gilmor from Compass Pathways. More details 👇

We have some exciting news to share from the Ye Lab! The first PhD student of the Ye Lab, Liina Sirvio, recently passed her PhD viva at Imperial College London! 🎉A big thanks to the excellent examiners Ed Tate and Catherine Lindon