#RealCase 40 yo male presenting pancytopenia and fever. Acute leukemia was suspected. After difficult #bonemarrow aspirate we found...#HairyCellLeukemia #Hemepath #Hematology #morphology

Dr. @DrSMBean presents today’s GR on career development and leadership Duke AHEAD Duke GME Duke University School of Medicine

Every so often a bone marrow comes along that makes me happy I don’t only do lymph nodes. 65 year old woman with macrocytic anemia and thrombocytosis. What’s your dx? #hemepath #bonemarrow

"Collagenous colitis- colon biopsy" in a 54 year old woman with watery diarrhea. Note the strands of collagen extending into the lamina propria from the basement membrane below the surface epithelium. #GIpath #TSPSpecialEdition. Case contributed by Dr. Saeed Vakili.

Here’s a nice case of soft tissue Rosai-Dorfman disease [R-group in the new classification scheme for histiocytoses; H&E, S100]. Clinically this was thought to be a cyst. #hemepath #bstpath #pathology

I would have missed this but I had a history.... oops.

Brent Tan Michael Cascio, MD beth margolskee Sanam Loghavi, MD صنم لغوی 🔬🧬 Rashmi Kanagal-Shamanna, MD SC @pwraess Kamran Mirza MD PhD - کامران مرزا Ameet Kini, MD, PhD @DitaGratzinger Julie Feldstein,MD Beth Vallangeon MD Genevieve Crane, MD, PhD Kyle Bradley, MD Daniel Babu, MD Chandra Krishnan, MD Chris Cogbill, MD The literature supports two different definitions of "atypical CLL". One is based on atypical morphology, such as cleaved cells or irregular nuclei. The second is cased on some "acceptable" variations of immunophenotype, such as expression of FMC7, minimal CD23, bright CD20...

Recommendations for the management of hemophagocytic lymphohistiocytosis in adults | Blood Journal bloodjournal.org/content/133/23…

ICCS is requesting submission of Case Study Interpretation (CSI) cases to be considered for publication in the ICCS eNewsletter and other online educational materials, or presentation at the ICCS annual meeting. Deadline is June 10, 2019 cytometry.org/public/csi-cas…

#VisualAbstract: The combination of the BCL2 inhibitor venetoclax plus obinutuzumab was more effective in the treatment of older medically ill patients with untreated chronic lymphocytic leukemia than was chlorambucil plus obinutuzumab. nej.md/2WOteHr

SAM jose garcia vela @mrinal90151372 Sanam Loghavi, MD صنم لغوی 🔬🧬 Expression of CD14 on promonocytes depends on the epitope, MY4 positive but MO2 negative according to Yang DT et al. AJCP. 2005;124:930-36. Of course neoplastic monocytic cells don't always follow these rules—sometimes you can even see CD14 on monoblasts. academic.oup.com/ajcp/article/1…

How do you handle agressive B cell lymphoma sign out when you are waiting on cytogenetics? Excellent advice from Dr. Hasserjian #ASCP2019 #hemepath

#SHEAHP2019 Our next case is a case of Lymph node involvement in myeloid/lymphoid neoplasm with PCM1-JAK2 by Dr. Nicholas Barasch, UPMC, Pittsburgh *Peripheral blood smear revealed leukocytosis *There was nodal effacement with erythroblasts

#pulmpath 🔬 🧩 60-ish yo woman with shortness of breath and bilateral pulmonary ground glass opacities. Thoughts? 🤔❓(big shout out to our amazing thoracic fellow Marina K Baine, MD, PhD for a spot diagnosis). Answer tomorrow. #natpathpuzzler

Had a great time working with Ameet Kini, MD, PhD on this project.

Morphologic heterogeneity in mast cell disease. Great presentation by Dr. Anton Rets from Utah. #SHEAHP2019 #hemepath

Dear patient, I carefully reviewed all the cells in your peripheral blood smear to make sure you don’t have leukemia. You’ll never meet me, but I care about you deeply. #IamYourPathologist

Dear Patient, I carefully reviewed millions of your bone marrow cells to make sure that you have no residual leukemia after treatment. You'll never meet me, but I care about you deeply. #IamYourPathologist

After looking at (many) bone marrow cases for cytopenias without morphologic features of dyspoiesis, you finally get a case that reminds you that you can still recognize dysplasia when its there. Nice example of prominent megakaryocytic dysplasia in a single 400x HPF. #hemepath