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Too much protein in the diet may carry a risk of heart disease secondary to leucine's effect. An important report considering recent advocacy for very high-protein diets. Nature Metabolism Babak Razani, MD, PhD Laboratory nature.com/articles/s4225…

Proud to host Eric Topol and Othman Laraki in conversation at Y Combinator today Topol is talking about new book Super Agers: what’s the key to healthy aging?

Tracking consumption of ultra-processed foods via metabolites in blood or urine journals.plos.org/plosmedicine/a…

The risk of sudden cardiac death among male bodybuilders academic.oup.com/eurheartj/adva…

Hey A.I., make me a protein Ewen Callaway nature nature.com/articles/d4158…

Less sedentary time among American adults jamanetwork.com/journals/jama/…

New nature An ingenious way to track DNA replication patterns at the single-cell level that leads to cell heterogeneity and daughter cells that can potentially give rise to cancer nature.com/articles/s4158…

Our A.I. times ;-)

Experimental evidence that post-stress sleep has the capacity to build resilience Neuron cell.com/neuron/fulltex…

A perspective on US Science The Economist economist.com/leaders/2025/0…

p-tau217 and other biomarkers for Alzheimer’s disease also tracked with loss of muscle strength in ~2,000 participants followed 12 years (Figures hand grip and chair-to-stand) thelancet.com/journals/lanhl…

A pill for sleep apnea that keeps the airway open Science Magazine Meredith Wadman science.org/content/articl…

"I have no time to sit too long. I'm happier when I can produce something."—Lee Rushall, age 98, a Super Ager In Chasing Life w/ Dr. Sanjay Gupta CNN w/ transcript cnn.com/audio/podcasts…

New Nature Aging Our body-wide pace of aging predicts healthspan and lifespan: outcomes of mortality, morbidity, cognitive impairment, and disability in US and UK cohorts nature.com/articles/s4358…

My conversation with Sir John Bell, one of the most influential physician-scientists in the world. The latest Ground Truths (link in profile), which is a hybrid of free analytic newsletters and podcasts (w/transcript)