Inaugural post! (after a long hiatus) Last May I quit my job to build Ditto Bio with Dennis Sun and Emily Weiss ! We turn parasite molecules into drugs for autoimmune disease, and are part of the Y Combinator W26 batch. Thanks for betting on us Ankit Gupta

🚀 So awesome to get to build together 🧬 (we need more parasite emojis here)

really excited about this team using viral/parasite biology to design new autoimmune drugs and develop immunogenicity models

Parasites do some really weird things to evade our immune system (see glycoproteins like ES-62) and are generally understudied, really cool idea

We found a parasite molecule that binds a major autoimmune target in the single-digit nM range. Even crazier, it ALSO hits another, completely unrelated immune regulator! It's a natural bispecific 🤩 Massive thanks to Adaptyv Bio for testing out our weird proteins. Let’s go !!

Every night before bed, I put on a plastic sock. It's part of treating my eczema, a condition I've managed for the last 6 years. It’s also one of the deeply personal reasons why I'm building Ditto Bio. 🧵 1/n