Alternative [2+2] for BCB scaffold via two sp3 CH and two ArX bonds, not starting from pi orbitals. Ligand innovation is the key: science.org/doi/10.1126/sc…

Escape from Palladium: Nickel-Catalyzed Catellani Annulation pubs.acs.org/doi/10.1021/ja…

Distance & geometry is emerging as key principle for ligand design to lower prohibitive TS. Molecular editing of saturated rings is made possible. Nature asap: rdcu.be/ddrPV. Licensed to the newly founded ArCHitect Therapeutics.

Bi-catalyzed radical catalysis with redox-active esters. Congrats to everyone involved! nature.com/articles/s4155…

Nature research paper: Photocatalytic phosphine-mediated water activation for radical hydrogenation go.nature.com/3NRRnXB

Check out our latest work in nature - Through leveraging frustrated radical pairs we accessed adaptive C-H activation using a variety of disilazide donors and N-oxoammonium acceptors, producing an array of alkoxyamines. nature.com/articles/s4158…

Our work describing Structural Editing of heterocyclic aromatic rings (thiophene) by insertion of cyclobutanes (from BCBs) is now out in Science Magazine Wild!🙃 Check it out: science.org/doi/10.1126/sc… Congrats to Ken Houk from UCLA Chem & Biochem and the Glorius Group from @WWU_Muenster

We published our first paper on pyridoxal radical biocatalysis in Science Magazine : lnkd.in/gkB5dpKM. What we are most excited about is the ability to design general biocatalytic activation modes which are both new-to-biology and new-to-chemistry:

Photoredox-active Cr(0) luminophores featuring photophysical properties competitive with Ru(II) and Os(II) complexes nature.com/articles/s4155…

Huge milestone for the group as our "Light Enabled Deracemization of Cyclopropanes by Al Salen Photocatalysis" is published nature! Congratulations to Carina, MorackLab, Julia, Olga, Niklas, @LichtMuck, Constantin G. Daniliuc & Johannes! @WWU_Muenster #OpenAccess nature.com/articles/s4158…

Developed H-donor catalyst for recruiting COOH, now H-acceptor catalyst for binding OH, Nature: 10.1038/s41586-023-06485-8. Enzymes can use multiple contact points to direct, we only have one, thus needs precise distance and geometry.Jacobsen Lab Hoveyda Lab Miller Group

Ever wanted a cross-metathesis … but with carbonyls? Check out Prof Lumin Zhang’s last discovery before starting his own lab at SIOC … in Nature Chemistry nature.com/articles/s4155… It’s like a reverse ozonolysis!

The final version of this study was published today in nature : nature.com/articles/s4158…

BREAKING NEWS The 2023 #NobelPrize in Physiology or Medicine has been awarded to Katalin Karikó and Drew Weissman for their discoveries concerning nucleoside base modifications that enabled the development of effective mRNA vaccines against COVID-19.

A Lewis acid-promoted visible light-induced intramolecular diradical-mediated HAT of primary, secondary, and tertiary C(sp3)−H bonds and subsequent cyclization of arylvinylpyridines to access various BCBs via energy transfer is online now in #OrgLett pubs.acs.org/doi/10.1021/ac…

Our first work! More DHATs are coming …

Out today in Chemical Science, we present a practical photochemical method for the preparation of alkenyl thiocyanates, unlocking new "S-alkenyl transfer reagents" for diverse organosulfur molecular assembly. Another great job by Helena Piedra! 👩‍🔬👏 pubs.rsc.org/en/content/art…

Thrilled to share our last work in collaboration with Yang XIONG just accepted in Angewandte Chemie on Visible light‐mediated [4+2] annulation of silylimines with olefins involving Diradical Hydrogen Atom Transfer (DHAT) of C−H Bonds onlinelibrary.wiley.com/doi/10.1002/an…

Our new development of Diradical HAT reaction! Israel Fernández Group excellent collaboration! 🎉🎉🍾

Visible Light-Mediated [4+2] Annulation of Silylimines with Olefins to 1-Aminotetralins Enabled by Diradical Hydrogen Atom Transfer of C-H Bonds (Yang Xiong and co-workers) Israel Fernández Group Yang XIONG • onlinelibrary.wiley.com/doi/10.1002/an…