Exciting news alert 🗣️📯: we are delighted to let you know that our 2023 disease models 🧫👁️🧠🫀🫁conference will be taking place on Wednesday the 8th of March at NEXUS. Please save the date and more details to follow soon ✍🏼

What a great opportunity for us to have Laura from SITrAN in Leeds today at the Leeds Centre for Disease Models annual conference. It was fantastic to hear about her groups' great research using induced neuronal cells to model neurodegenerative conditions.

Great to see this paper out from Christopher Watson and LeedsVisionResearch on the use of long-range Oxford Nanopore sequencing to verify and characterise large deletions identified from exon-based short-read sequencing. Rare Disease @ Leeds #nanopore #RareDisease onlinelibrary.wiley.com/doi/10.1002/mg…

Register to hear about our #zebrafish models of #leukodystrophy and an intro to LEUKOLABS to boost UK #leukodystrophy research and collaborations!

Our latest paper is now online Genetics in Medicine! We identified and characterised de novo missense mutations in RRAGC as a cause of a fatal mTORopathy of early childhood. Thanks to all collaborators, particularly @ReijndersMargot and Felix Distelmaier. sciencedirect.com/science/articl…

De novo missense variants in RRAGC affecting MTORC1- and TFEB-signaling cause an early #mTORopathy with unfavorable prognosis #mtor #cardiomyopathy #corticalmalformation bit.ly/3mI1lQk

Excited to be speaking about the human brain on the 24th May at the Nation of Shopkeepers in Leeds for Pint of Science UK #Pint23 Neuroscience in Leeds. See the full line up and buy tickets here: pintofscience.co.uk/event/mind-won…

Recruiting a technician to join my lab Biology at York York Biomedical Research Institute - ideal for recent graduates who need to boost their lab skills to apply for PhD! Learn about #zebrafish models of brain diseases #leukodystrophy #neuroimmunology in a friendly/supportive lab jobs.york.ac.uk/vacancy/resear…

We're delighted to be hosting Dr Chris Tape (Chris Tape) on 21st June to speak about Single-cell Signalling Analysis of Tumour Microenvironment Organoids, followed by lunch provided by Leeds Centre for Disease Models. Register using the QR code below or at tinyurl.com/LCDMseminarDrC….

Our very own James Poulter from Molecular Neuroscience Group @ Leeds will be at the Nation of Shopkeepers in Leeds on Wednesday evening talking about what's inside the human brain for Pint of Science UK #Pint23. Rare Disease @ Leeds Neuroscience in Leeds UK Research and Innovation #UKRIFLF

HIRING! I am looking for a computational biologist to come and help cure brain cancer and progress this work: biorxiv.org/content/10.110… Apply by 7th July here: jobs.leeds.ac.uk/Vacancy.aspx?i… The role is highly likely to be extended beyond Sept '24 NorthernBUG Glioma Genomics Research Group Leeds'Omics

HIRING! We need an experienced computational biologist 💻🧑‍🔬to join us & work on cutting-edge brain cancer datasets🧠🧬The post is funded until Sept '24 but with v.high chance of extension until July '25 & then 3 year renewal! Apply here: jobs.leeds.ac.uk/MHLMR1124 before 26th Sept!

Interested in lncRNAs, brain organoids and long read nanopore sequencing? julie aspden, Thomson Lab and I have an exciting PhD project that includes all of these!! Apply using the link below...

We are recruiting! Lecturer in Neuroscience: Interested in working with other enthusiastic neuroscientists Neuroscience in Leeds . Check out the link: jobs.leeds.ac.uk/Vacancy.aspx?r… Application deadline: 17th Nov 2023

🎉EXCITING OPPORTUNITY to do a PhD 🎓in single cell brain cancer bioinformatics 🧠🧬👨‍💻! Co-supervised by @rachelq_ncl. Project details are here: tinyurl.com/AmazingPhDoppo… & scheme info & how to apply: tinyurl.com/InfoAndApplica… Deadline to apply is 17th Dec 👀

Exciting opportunity for a motivated PhD student to study biology of #VEXAS syndrome and explore new treatment strategies with support of industry partner findaphd.com/phds/project/m…

New Nature Medicine paper from Boston Children's Wellcome Sanger Institute and York Biomedical Research Institute on clonal dynamics of HSCs pre- and post-gene therapy. 👍 @AlyssaHCull Mike Spencer Chapman 👍 Gracious for both the funding and the network connectively from Gates Foundation nature.com/articles/s4159…

📢New AJHG 📰A recurrent de novo MAX p.Arg60Gln variant causes a syndromic overgrowth disorder through differential expression of c-Myc target genes 🧑‍🤝‍🧑James Poulter & colleagues cell.com/ajhg/fulltext/…

Great start to 2024 with our publication describing a recurrent de novo in MAX associated with a syndromic form of macrocephaly and polydactyly in AJHG. Thanks to all our collaborators who contributed to this work and funding from UK Research and Innovation. cell.com/ajhg/fulltext/…

From the first report of successful pregnancies after treatment with Alpelisib for PIK3CA-related disorders nature.com/articles/s4143…