Congrats to Yael Gruper our incredible PhD student for presenting her novel study on tooth autoimmunity!👏😎

A well deserved break from the lab :) Had an incredible time together in the lowest place on earth 🌍 Thank you The Immunology and Regenerative Biology Department for a great retreat!

Congratulations to Czech Young Immunologists for organizing a fantastic mixer event and for kindly inviting me to be part of it. So happy to see Czech immunology blossoming again…

NEW Review: The emerging family of RORγt+ antigen-presenting cells bit.ly/3OtuSbP by Greg Sonnenberg Abramson Lab Mengze Lyu Jan Dobeš summarizes the major findings that led to their discovery and discusses discordance in recent reports

dlvr.it/SsXgH8 I am very privileged to write this Nature Rev Immunol review on RORγt+ APCs together with G Sonnenberg Mengze Lyu Jan Dobeš.  We review their history, molecular & functional complexity, while also highlighting existing unknowns and future perspectives

Applications for the 2024-25 Azrieli Int’l #Postdoctoral #Fellowship are OPEN! Apply by Nov 15 to be considered for a postdoc position at a top academic institution in Israel – available to candidates worldwide. Learn more: bit.ly/3YSBmV7 #CallforApplications

We are very happy to share our lates publication in nature, spearheaded by Tal Givony &Yael Goldfarb, expanding the incredible cellular & functional diversity of mTECs and bringing key insights into the roles of thymic microfold and endocrine cells nature.com/articles/s4158…

In Journal of Experimental Medicine, Tomáš Brabec, Schwarzer Martin, Abramson Lab, Filipp Lab, Jan Dobeš et al. show that segmented filamentous bacteria induce the conversion of cognate CD4+ T cells to cytotoxic intraepithelial lymphocytes. bit.ly/3tQJSbM Faculty of Science of Charles University

New paper out today in Journal of Clinical Investigation! A new splice mutation of Aire that skips exon 7, shows a correlation between Aire function and degree of disease. Ex7splice retains some function, giving milder disease phenotype in compared to recessive variants jci.org/articles/view/…

Our medRxiv is open for public comment. We describe the experience of people reporting a chronic post-vaccination syndrome (PVS) after covid-19 vaccination. We are following the science. Prof. Akiko Iwasaki React19 Yale School of Medicine Yale Center for Infection and Immunity medrxiv.org/content/10.110…

Could the consumption of milk lead to dental problems in some children? New research led by Prof. Jakub Abramson and his team has uncovered a new autoimmune disorder that affects the development of tooth enamel and is prevalent among children with celiac disease. While many

Thymus regeneration upon glucocorticoid-induced acute involution is orchestrated by IL-25– and IL-33–dependent activation of ILC2 Science Immunology science.org/doi/10.1126/sc…

Congratulations to Jan Dobeš for being awarded the FGS prize for outstanding achievements in postdoctoral research!

Very happy to share our latest ⁦Science Immunology⁩ paper spearheaded by Shir Nevo uncovering the role of thymic fibroblasts and tuft cells in thymus regeneration upon acute injury science.org/doi/10.1126/sc…

The thymus can regenerate after acute injury due, in part, to the actions of local type 2 innate lymphoid cells (ILC2s), suggests a new study in mice. Weizmann Institute 📄: scim.ag/5wr

Congratulations to Prof. Jakub Abramson Abramson Lab of the Immunology and Regenerative Biology Department and to Drs. Einat Segev and @filipenatalio of the Plant and Environmental Sciences Department upon receiving the European Research Council (ERC) 2023 Proof of Concept Grant #ERCPoC

In this study, interferon-γ was found to play a large role in the pathogenesis of APS-1. Results were confirmed in studies in animals and led to a trial of ruxolitinib in five patients, who had dramatic responses. Read the full study results: nej.md/4bXoKkG

Happy to see our story on tolerance to inflammation antigens Nature Immunology nature.com/articles/s4159… It grew from a naive question I had at my first immunology class: if some self molecules are only induced by pathogen how does immune system distinguish them from foreign antigens?1/n

The recorded video of Dr. Jakub Abramson seminar entitled Breath of fresh AIRE - From broken central tolerance to broken teeth and anti-fungal immunity is now available at “Global Immunotalks” YouTube Channel youtu.be/uVxcC6q5ewo?si…  Hope you enjoy it! #globalimmuno #immunology