Comprehensive and insightful review by Prat Lab discussing the role of genes & environment on BBB disruption in MS and the therapeutic implications of mesenchymal stromal cells and antibodies targeting cell adhesion molecules or #fibrin to halt neurodegeneration. The Lancet Neurology…

In our January 2024 issue: the blood–brain barrier in multiple sclerosis, reviewed by Bettina Zierfuss and colleagues from Prat Lab thelancet.com/journals/laneu…

Please share! The 2024-2025 #endMS_SPRINT and 2024 #endMS_SummerSchool competitions are NOW OPEN! Inviting graduate students, post doctoral and clinical fellows, to apply by Feb 15, 2024. For complete details: endmstrainingprogram.ca Christina Wolfson MS Canada University of Manitoba

Excited to be part of MS Canada #EndMS 2023 in Toronto! I’m grateful for the chance to engage with the MS research community. I’ll be presenting the latest work on cytokines and endothelial barriers in the brain from the Prat Lab with my poster #97 at 17:15, let’s connect!

In this week’s #neuroimmunology special issue, Thai and Prat Lab explore advances in immune cell carriers that ferry therapeutics across the #BloodBrainBarrier , which are opening a new frontier in #DrugDelivery for central nervous system disorders. Centre de recherche du CHUM scim.ag/4PP

Check out our recent Viewpoint 👇

Hoping to spread the word: We've started a study to see how circadian rhythms might affect those living with MS in Canada. Please share/RT across your networks! Soheila Karimi-Neural Regeneration & Stem Cell Jason Plemel UAlberta MS Centre The Neuro DCNS Calgary Prat Lab Craig Moore uOBMRI Raphael Schneider Unity Health Toronto

Very thrilled to have had the opportunity to present my PhD work in the Prat Lab about the use of single-cell immune profiling for prediction of MS activity today at ECTRIMS #MSMilan2023 🧠

Leucocyte trafficking inhibition to modulate neuroinflammation: is MCAM a next generation target (and more clever than Natalizumab)? A commentary on novel findings and strategic thoughts around this: pubmed.ncbi.nlm.nih.gov/36946303/

Interested in exciting research on the BBB and MS? 🧠 The Prat lab is recruiting talented and motivated graduate students and post-docs! DM us to know more about available positions and send applications to [email protected]. Please share!

If you’re interested in machine learning, come see my poster p290 ‘Machine Learning Identifies a Combination of Immunological and Clinical Parameters as the Best Predictor of MS Disease Progression’ at the #ACTRIMS2023 poster session tonight! #MultipleSclerosis Prat Lab endMS Training Program

Which endothelial cell types are most responsive to neuroinflammation?
Read our new article to find out and feel free to play with the two interactive R shiny applications to identify new targets for your projects.
nn.neurology.org/content/10/1/e…

Read more about our latest story published in Brain about the role of MCAM+ brain endothelial cells in the recruitment of pathogenic T cells in multiple sclerosis!

Check out our recent study led by Antoine Fournier: CLMP Promotes Leukocyte Migration Across Brain Barriers in Multiple Sclerosis nn.neurology.org/content/9/6/e2…

The Prat lab is recruiting graduate students! Please share and send your application to [email protected] if interested. More info about the research here: neurosciences.umontreal.ca/recherche/les-…
Centre de recherche du CHUM Université de Montréal

Our latest paper is out! The first 'official' research paper of my beautiful CBN team Universiteit Hasselt, with Doryssa Hermans 🌈 as first author (but this publication was a team effort!).
Check it out! Especially if you're into #bloodbrainbarrier #multiplesclerosis
👇👇👇
link.springer.com/article/10.100…

Such a great talk from Dr. Jen Gommerman today at the Centre de recherche du CHUM! #BCells #Aging #GreyMatter #WomenInSTEM

Check out the most recent publication from the Yong lab led by our talented Jeff Dong on how age impacts microglia's capacity to buffer CNS damage!
nature.com/articles/s4358…

Huge congratulations to our PhD student Karine T for the best presentation award in the ADENUM last event! 🥳🤩 we're so proud of you!

4-year-old Victoria has already read 161 books since January 27th for @MSSocietyCanada's Read-A-Thon, in honor of her grand-mother Monique, who has been living with MS for many years. Congratulations Victoria! To encourage her efforts👇msreadathon.ca/fundraisers/Vi…