Excited to share our new paper in AJPC: Aspirin Use for Primary Prevention Among US Adults With and Without Elevated Lp(a)

sciencedirect.com/science/articl…

Regular aspirin use was associated with a 52%⬇️ risk of ASCVD mortality among adults without ASCVD and Lp(a) ≥50 mg/dL

Q: What is the CV benefit of icosapent ethyl across a range of Lp(a) levels?

A: Icosapent ethyl was associated with reduced MACE outcomes across a range of Lp(a) levels

Read more in #JACC : bit.ly/4aUTF0E #cvPrev

Interesting JACC Journals article about possible mechanism of #SGLT2i benefit in HF.

Perhaps the benefit is not in osmotic diuresis, but instead '“nutrient deprivation signaling/autophagy hypothesis” via 'reprogramming of mitochondrial function.'

jacc.org/doi/10.1016/j.…

Today is #WorldChagasDiseaseDay , so we invite you to read our 2018 #guideline , 'Recommendations for Multimodality Cardiac Imaging in Patients with Chagas Disease!' bit.ly/3zZEkeJ #ChagasDisease

Attending discussion by Dr Patrick O’Gara, when to intervene in asymptomatic severe aortic regurgitation. Data clearly shows volumetric analysis of LV dilatation (LVESVi 45 ml/m2) on echo and cMRI outperforms linear measurement. #ACC24 American College of Cardiology

In patients post ACS, treatment with ticagrelor monotherapy after 1 month of DAPT was non inferior to DAPT for prolonged duration. #ACC24 #ULTIMATE -DAPT American College of Cardiology Gregg W. Stone MD

Lifetime event risks for a 45 year old patient with mechanical vs bioprosthetic vs Ross procedure with Dr Isaac George #ACC24 American College of Cardiology

Dr Wael Jaber discussing TAVR vs SAVR in young patient with aortic stenosis. Complex decision needing multi modality imaging with CT and echo #ACC24 American College of Cardiology

Benefits of rapid initiation of quadruple GDMT new diagnosed HFrEF

12 month mortality rates

Quad GDMT vs no GDMT
ARR 24.8%, NNT=4

Quad GDMT vs ACEI/ARB+BB
ARR 10.4%, NNT=10

sciencedirect.com/science/articl…

🚨Today is Lp(a) Awareness Day!
Let's use our voices to shed light on the significance of Lp(a) testing. Early detection can be pivotal in preventing cardiovascular diseases. Join us in ensuring everyone knows why it's crucial to #KnowLpa Family Heart Foundation
ow.ly/3CSf50R0ssI

Dr. WilliamZoghbi presenting echocardiographic approach to understanding prosthetic mitral valve function, as discussed in the 2024 American Society of Echocardiography prosthetic valve guidelines: asecho.org/wp-content/upl… #EchoSOTA

Enjoying discussion of an interesting and challenging case of asymptomatic severe aortic stenosis with Dr. Rick Nishimura at the American Society of Echocardiography State of the Art Echo course #SOTAEcho

Using clopidogrel (thankfully generic) after 1 year post-PCI may reduce ischemic events (CV death, MI, stent thrombosis or stroke)- 28% ischemic risk reduction at 5 years, and could be a good option in those patients at average or lower bleeding risk. JACC Journals #STOPDAPT2

Rapid up-titration of #Entresto and #SGLT2 inhibitor (along with evidence based beta blocker and MRA) in patients with #heartfailure with reduced EF- effects are complementary and additive. Start ASAP- curves separate early. #QuadrupleTherapy #DAPAHF Gregg Fonarow MD

Looking forward to closely reviewing these new guidelines. There is a helpful chart describing potential deterioration of structural valve- using a combination of mean gradient AND decrease in EOA, as an example, and/or a decrease in DVI, compared to baseline. #echofirst American Society of Echocardiography

Tricuspid regurgitation is a challenging issue, often in patients with multiple co-morbidities. In those patients with severe TR who are not surgical candidate, T-TEER (edge-to-edge transcatheter repair) is a useful option to improve quality of life.