Congrats to Yoojoong Kim Ryan Gumpper Bryan Roth

Bitter taste receptor activation by cholesterol and an intracellular tastant
nature.com/articles/s4158…

Now congrats to Dr. Yu-Chen Yen on her totality cool structures of AC5! Yu-Chen took a gamble on this project, but she was never one to resist a challenge. With Carmen Dessauer & the Watts lab. Just published with Springer Nature in @NATURESMB. Read here: rdcu.be/dD5UL

Excited to share our preprint on a new centriolar kinase-phosphatase module, with fantastic U-ExM microscopy by Paul & Virginie - Centriole Lab and Armando R! biorxiv.org/content/10.110… Here we studied Ppp2r3c, a PP2A phosphatase regulatory subunit and hit from our prior cilia CRISPR screen…

Congrats Dr. Chung-Liang Chen! A monumental effort to see how hetG proteins bind and regulate PI3Kgamma, and thereby control chemotaxis and metastasis. With a great assist from Deng Lab.
Just published with Springer Nature in @NATURESMB. Read here: rdcu.be/dDlEV

🚨Out in Molecular Cell, “Molecular Determinants and Signaling Effects of PKA RIα Phase Separation” by Julia C. Hardy establishes that a non-canonical, active PKA R:C complex in RIα condensates sequesters PKA activity from the cytosol. tinyurl.com/MolDetRIa

So excited to see our work on 'Profiling the proximal proteome of the activated μ-opioid receptor' using APEX-based proximity labeling and quantitative mass spec published today. It is the result of an amazing team effort!
nature.com/articles/s4158…
#TeamMassSpec #Proteomics #GPCR

Our ASBMB #DiscoverBMB session on cell signaling and protein phase separation starts at 2:45. Come for great talks and panel discussion!

Chuck was a brilliant and kind scientist. He will be missed. 💔

Very happy to have my recent work on 'Time-resolved cryo-EM of G protein activation by a GPCR' out in Nature today! #cryoEM #GPCR nature #LabSkiniotis nature.com/articles/s4158…

Very excited to share our most recent publication: sciencedirect.com/science/articl…. Do you like GRKs and the GLP-1R?! Then this paper might be worth a read (1/n).

Join us in the Twin Cities May 12-16th 2024 for the FASEB Biology of the Cilia and Flagella meeting! Exciting science, great community, and grants to help everyone attend. Please retweet, cilia peeps! Register here:
events.faseb.org/event/895c8ffa…

Today we remember and celebrate the life of Bill Weis. Our friend, colleague, & mentor. We scientists are lifelong learners by temperament & necessity. Bill fueled our learning daily. 1/n

Wild!

Excited to share our work published in
Nature Communications.
This was a joint collaboration between the Bernhard lab, Arne Moeller and my lab with great help from the Kolb lab, Steffen Pockes, Hannes Schihada, PhD, Margherita Persechino and others.
rdcu.be/dzSNl

Do you want to measure #GPCR activity directly, easily and in your favorite cells? We hope this paper will help. Opus magna led by PhD extraordinaire Remi and former powerhouse postdoc Marcin. Free 50 day access
authors.elsevier.com/a/1ifn4L7PXqPgF
sciencedirect.com/science/articl…

Wow this paper is super cool 😍 congrats Mikel Garcia-Marcos Laboratory + Joseph C Wu, MD, PhD and all 👏

cell.com/cell/fulltext/…

Check out our new review article on ciliary signaling, now online at Nature Reviews Molecular Cell Biology - a great collaboration with Keren Hilgendorf and Reiter Lab!

Our latest review article in NRMCB is out on everyone's favorite signaling organelle, the primary cilium!
It was truly a real pleasure to work on this with Ben Myers Lab and Reiter Lab.

There are scientist birds and scientist frogs. The birds delight in unifying concepts, while the frogs delight in the details of particular objects. Science is rich and beautiful because birds give it broad visions and frogs give it intricate details. (Paraphrasing Freeman Dyson)