'The concept of resilience to #AlzheimersDisease : current definitions and cellular and molecular mechanisms'

Luuk E. de Vries, Inge Huitinga, Helmut W. Kessels, Dick F. Swaab, Joost Verhaagen NIN

bit.ly/49usBnN

⏰ Early Registration for ISMND 2024 ends on Wednesday April 10!

Register now for discounted prices...and let's not forget, ISMND members get extra registration discounts too!

ISMND 2024 Registration: bit.ly/4azOK5N
ISMND membership: bit.ly/464WF9g

I am thrilled to share exciting data (Molecular Neurodegeneration) showing that regulatory T cells (Treg) are essential for healthy retinal ageing. This discovery paves the way for further exploration into the involvement of Treg in age-related diseases!

'An adapted protocol to derive #microglia from stem cells and its application in the study of #CSF1R -related disorders'

Marie-France Dorion, Diana Casas...Roberta La Piana Luke M. Healy The Neuro McGill University #iPSC

bit.ly/3PMMfEA

Researcher Alerie Guzman de la Fuente (@NeuroAlc & ISABIAL) has co-led a study that has just been published on Molecular Neurodegeneration 👏
This work shows that Treg cells are key for maintaining retinal homeostasis and preventing retinal inflammation and neurodegeneration with age.
More details🧵👇

Delighted to share our latest article published in Molecular Neurodegeneration where we show that despite the low number of regulatory T cells (Treg) in the retina, they are key for maintaining retinal homeostasis with age …arneurodegeneration.biomedcentral.com/articles/10.11…

'Regulatory T cells limit age-associated #retinal #inflammation and #neurodegeneration '

Llorian-Salvador Alerie Guzman de la Fuente... Alan Stitt Denise C. Fitzgerald Wellcome-Wolfson Institute Experimental Medicine Queen's University Belfast 🎓 Instituto de Neurociencias UMH-CSIC

bit.ly/49ulawS

'The endotoxin hypothesis of #AlzheimersDisease '

Guy C. Brown Cambridge University & Michael T. Heneka uni.lu #microglia #neuroinflammation

bit.ly/49i2hNJ

🚨UPDATE🚨 All abstract applicants should have received notification of their presentation type and travel fellowship status via email

If you have not received said emails, please check your junk folder first before contacting us.

We look forward to welcoming everyone to Seoul!

'HDGFL2 cryptic proteins report presence of #TDP43 pathology in #neurodegenerative diseases'

Anna Calliari, Lillian M. Daughrity...Michael Ward (he/him/his) Yong-Jie Zhang, Leonard Petrucelli Mayo Clinic Neuro NIH

bit.ly/3IXKOPX

Correction: Unravelling cell type-specific responses to Parkinson’s Disease at single cell resolution

…arneurodegeneration.biomedcentral.com/articles/10.11…

Correction: Blood–brain barrier-associated pericytes internalize and clear aggregated amyloid-β42 by LRP1-dependent apolipoprotein E isoform-specific mechanism

…arneurodegeneration.biomedcentral.com/articles/10.11…

Our Managing Editor Lucy Job hosted an International Society for Molecular Neurodegen. Science Webinar with Dr. Sandro Da Mesquita today!

Interested in learning more? Find Dr. Da Mesquita's MN review 'Current views on #meningeal #lymphatics and immunity in aging and #AlzheimersDisease ' here... bit.ly/3KFtctv

'A partial Drp1 knockout improves autophagy flux independent of #mitochondrial function'

Rebecca Z. Fan, Carolina Sportelli...Kim Tieu FIU #Parkinsons #autophagy #synuclein #MitochondrialDysfunction

bit.ly/4amIMof

'Rejuvenating aged #microglia by p16ink4a-siRNA-loaded nanoparticles increases #amyloid -β clearance in animal models of #AlzheimersDisease '

Hyo Jung Shin...Dong Woon Kim - Chungnam National University College of Medicine #senescence

bit.ly/3IFl76v

We are delighted to announce Sandro Da Mesquita Ph.D. Sandro Da Mesquita Mayo Clinic Neuro as our next ISMND webinar speaker!

Title: Regulation of brain #myelination by the #meningeal #lymphatic system

March 21, 2024
10-11am (EDT)

Host: Lucy Job
Register: bit.ly/3v2zE9l

⏰⏰ Only a few days left to submit an abstract for a short-talk or poster presentation for our hybrid meeting ISMND 2024, in Seoul, South Korea!

Deadline: March 15, 2024

Travel & Diversity Fellowships are available!

Find more details at: ismnd2024.org/abstract

' #APOE 4 genotype and #aging impair injury-induced #microglial behavior in brain slices, including toward Aβ, through P2RY12'

Jordy Sepulveda...G. William Rebeck Georgetown University #AlzheimersDisease #APOE

bit.ly/49JS91p

'Updates on mouse models of #AlzheimerDisease '

Michael Z. Zhong, Thomas Peng Dr. Mariana Lemos Duarte Minghui Wang, Dongming Cai Dongming Cai, MD, PhD Icahn School of Medicine at Mount Sinai University of Minnesota Mount Sinai Neurology

#amyloid tau #TREM2 #APOE

bit.ly/3v9nIm3

'GBA1 inactivation in #oligodendrocytes affects #myelination and induces #neurodegenerative hallmarks and lipid dyshomeostasis in mice'

Ilaria Gregorio Loris Russo...Matilde Cescon Università di Padova #Parkinsons

bit.ly/4a29FxA