What's the chance you might get Alzheimers? The DNA map of 23 and Me includes your ApoE2, OR ApoE3 and/or ApoE4 (inflammatory pro-Alzheimer's alleles: 2 ApoE4's = ~50% chance). Download 'All DNA'-(looks like genome_your name_Full_date.zip & send to a website such as Promethease.

ما يقارب ٢٥٪ من الناس يحملون جين يسمى APOE4 لكن لا يعرفون

أدمغة حاملين الجين أصغر من الآخرين (بالأخص من يحملون نسختين منه ونسبتهم ٢-٣٪)

كما أن نسبة اصابتهم بالزهايمر ترتفع الى الضعف

الطريقة الوحيدة لمعرفة اذا كنت من من يحملون هذه النسخة هي الفحص الجيني

Um dos filhos de Chris Hemsworth, assim como ele, também tem duas cópias do gene APOE4, o que não é um diagnóstico de Alzheimer mas sim uma probabilidade que pode ou não se concretizar.

El uso prolongado (>4.4 años) de inhibidores de bomba de protones (p. ej. omeprazol):
⬆️ el riesgo de demencia en adultos mayores (promedio de edad 75.4 años) en un 33-42% 🧠
🔴Esto considerando otros factores de riesgo de demencia como la edad, APOE4, hipertensión, diabetes,

If you're familiar with the world of #dementia & #Alzheimers , you're definitely familiar with the #APOE #gene . But did you know there's several variants - #APOE 2, #APOE 3, #APOE 4 - one of which actually helps to protect against #AD ?😲🧠🔬
stan.md/46rUdIE
#brainhealth

He did generic testing and found out he has two copies of APOE4 (I only have one copy) which is highly correlated with Alzheimer's so he quit acting and is just doing endurance running all day now.

One man vs his genetics. A sci Fi story

Let's see what happens

I'm thrilled to share my first postdoc preprint!

We find that the #Alzheimers risk gene #apoE4 significantly impairs lysosomal function in neurons. We use LysoIP and MS to highlight 2 proteins causing this, and target them to modulate #lysosome function.
biorxiv.org/content/10.110…

ALZHEIMER'S DISEASE & GENETICS

Having 1 ApoE4 allele increases risk 2-fold

Having 2...

That increases risk up to 10-fold

Dr. Rhonda Patrick

What does the 'Alzheimer’s gene' reveal about the link between Alzheimer’s disease and cholesterol transport in the body?

In 1990, the Human Genome Project began to map the DNA instructions in human cells. This led to discovering the APOE4 gene’s link to higher Alzheimer’s risk.

Alzheimer hastalığında yeni ruhsat alan Lecanemab ile tedavi edilen, iki APOE4 aleli olan 79 yaşındaki kadın hasta..

Üçüncü uygulamadan sonra başlayan, şiddetli ARIA ilişkili beyin iltihabı nedeniyle steroid tedavisine rağmen 5 gün sonra hayatını kaybetmiş📌

Living With The High-Risk Alzheimer’s Disease ApoE4 Gene [Video] – Neuro Support Giving

Living With The High-Risk Alzheimer’s Disease ApoE4 Gene [Video] – Neuro Support Giving

Living With The High-Risk Alzheimer’s Disease ApoE4 Gene [Video] – Neuro Support Giving

Join us for ApoE4 Awareness Week, ending on April 30. Learn, share, and support genetic health awareness! #ApoE4 #Awareness #HealthGenetics #internalmedicine #meridianms #mississippihealthcare

How does the brain metabolism of the omega-3 DHA change across the lifespan in individuals carrying the APOE4 allele? Credit to the talented Brandon Ebright for leading this review. Keck School of Medicine of USC , #USCMann , #Alzheimers , #APOE4
sciencedirect.com/science/articl…

Araştırmada insanların sosyoekonomik durumları, sağlık durumları ve APOE4 genleri de göz önünde bulundurulmuş.

Sağlıklı beslenme hafıza kaybını en çok yavaşlayan davranış. Bunu zihinsel aktiviteler ve düzenli egzersiz izliyor.

Cell type-specific roles of APOE4 in Alzheimer disease
👉nature.com/articles/s4158…

著名期刊Nutrients上刊登一篇研究发现，血液中DHA水平较高的人患阿尔茨海默症的可能性比水平较低的人降低了49%。而饮食中额外提供DHA，可降低痴呆的风险，尤其是对于携带ApoE4基因（痴呆高危人群）的人，可减缓疾病的发展。youtu.be/0MwiHr5GGV8?si…

Pesquisa confirma a influência de gene na progressão da doença de Alzheimer

Artigo de João Pedro Ferrari Souza, doutorando do PPG Bioquímica da UFRGS, demonstra pela primeira vez em humanos que a variante APOE4 contribui para o acúmulo da proteína tau: bit.ly/455o1dp

Baseline characteristics for $sava simufilam P3 studies well matched. #apoe4 carriers right at 60% that exists in AD. 71% of patient in the trial were Mild AD. Given historical data on the 24 OLE mild patients, this all but guarantees rethink will achieve statistical