I am thrilled that our paper on kidney cancer is now out in nature!!! nature.com/articles/s4158…

Pop it in your diary for next week!

Big news, Nowosad Lab is hiring a technician! Come and help us figure out how B cells tell friend from foe in the intestine. You can message me, check out our lab website, or apply here > jobs.nyulangone.org/job/20205972/r…

Interested in learning more about the many functions of Reactive Oxygen Species in cancer? Check out our recent review in Nature Cancer. Special thanks to Kat who in collaboration with Ahmed and Volkan Sayin Group put together this comprehensive review article nature.com/articles/s4301…

Very excited to share our latest preprint on somatic mutations in the normal stomach. We found many surprises, incl. hypermutant glands, recurrent somatic trisomies and a unique landscape of driver mutations. Thread below! biorxiv.org/content/10.110…

Children who develop two independent tumors during childhood are extremely rare. We wanted to shed light into those exceptional cases using genome analysis

We also reveal the mutational footprint of chemotherapy in normal tissues using duplex sequencing of autopsy samples

👇

Now online! APOBEC3A and APOBEC3B drive distinct mutational landscapes in tumors. We showed how A3A and A3B substrate preferences for different hairpin structures can be exploited to identify patients' tumors with mutations caused by either A3A or A3B. nature.com/articles/s4146…

Odličan primjer su prilike naše mlade znanstvenice Mije Petljak Mia Petljak koja je nedavno otvorila svoj lab na NYU Grossman Medical School i traži postdoktoranda, senior znanstvenika, i čak remote interne iz područja bionformatike!

#internships #postdocs #jobopportunity

How did we lose our tail? A simple question.. but it wasn't really asked before! We discovered a plausible scenario for the genetic mechanism that led to tail loss. Amazing that such a big change may have been caused by such a small genetic event. nature.com/articles/s4158… Bo Xia

Congratulations to Eleonore Toufektchan and all co-authors on our new study showing how TREX1 guards against anti tumor immunity by degrading cytosolic DNA to limit cGAS-STING! Great collaboration with the Samuel Bakhoum lab.

Our paper is out today in nature! Imagine getting this plot when studying single-cell data of growing bacteria! Could it be the cell cycle?! We found that a gene’s response to its replication reveals gene regulation on a genomic scale.
nature.com/articles/s4158… Andrew Pountain

Too cool!!! Wowza

The first genome sequence of a human cancer was reported 15 years ago. As Sheng Cai & Ross Levine discuss, this ushered in a new era of diagnostic, prognostic and therapeutic advances. go.nature.com/40TFhlD

It was a pleasure to present our research and our new lab at #EMBLCanGen

Fantastic conference, great colleagues, so much fabulous research. Thank you organizers Nuria Lopez-Bigas Young Seok Ju and others. Highly recommend!

If you're interested in mutational signatures and somatic evolution, Mia Petljak's team NYU Grossman School of Medicine is hiring postdocs and senior scientists!! Go write to her 😀

BIG DAY - First pipettes have arrived to the the lab !!! 🤩🍾

(gloves have clearly not 🫣)
#NewPIjoys

out today in Nature Genetics 🎉!!! our study applying a simple physical principle (mass balance) to deconstruct the notion that you need long reads to detect large variants in cancer nature.com/articles/s4158… 1/🧶

Another seminal contribution from Marcin Imieliński and his group. Mass balance, short-read whole genome data and the mapping of cancer chromosomal structure. NYU GSOM Pathology Perlmutter Cancer Center at NYU Langone Health
nature.com/articles/s4158…

📢 Our team at NYU has grown but we have more positions open!

🟢 Senior Scientist ~65-89k

🟢 Team: petljaklab.com

🟢 Where: launching NYU Grossman School of Medicine premier lab spaces in CURE building (cure.345pas.com)

🟢 Apply: nature.com/naturecareers/…

'Effects of psoriasis and psoralen exposure on the somatic mutation landscape of the skin' nature.com/articles/s4158…