Delighted to see this - it represents a painstaking development of. a method by Fay Allen, overseen by Andrew James. This will hopefully be useful to the field - in metabolomics speed of isolation is (nearly...) everything... FEBS Press febs.onlinelibrary.wiley.com/doi/10.1002/18…

I’m excited to share a new #cancer #metabolism preprint where we explore nutrient transport in cells and tumors in CRISPRi/a screens. biorxiv.org/content/10.110… Our question: How do small molecules like nutrients and drugs get in and out of cells? 🧵(1/12)

WE HAVE WON OUR UNION WITH 97% VOTING YES!!! 🔥🔥🔥

BACTERIAL HUNGER GAMES E. coli and V. cholerae participate in a biofilm. But E. coli persuades the V. cholerae to occupy the outside layer, where they get eaten by a third predatory bacteria, Bdellovibrio bacteriovorus, while the hiding E. coli live on. pnas.org/doi/10.1073/pn…

#NatMetabPicks | In Cell Metabolism, Takeuchi et al. (RIKEN) evidence abundance of a commensal species of the family Lachnospiraceae during obesity & hyperglycemia, produces LCFAs & facilitates diet-induced obesity. cell.com/cell-metabolis…

Genetic mapping of microbial and host traits reveals production of immunomodulatory lipids by Akkermansia muciniphila in the murine gut nature.com/articles/s4156…

new out in Nature today nature.com/articles/s4158…

Midwesterners can smell this picture

ICYMI 👀 Gut microbial metabolism of 5-ASA diminishes its clinical efficacy in inflammatory bowel disease Nature Medicine nature.com/articles/s4159…

Insane paper Ketogenic diet suppresses th17 cell.com/cell/fulltext/… #campbellneurosciences $tsoi

A short thread about Adam Dowdell's excellent chemotaxis paper, just out in Current Biology. It shows how combinations of ligands for the same receptors cause fascinating & counterintuitive outcomes (1/n) cell.com/current-biolog…

Very excited and proud to see this work finally published! Juan José Apiz Saab (he/him) is a science rockstar and I'm proud to be first co-authors together! Grateful as well for the many others who played a huge part in making this possible! Cheers everyone!

New paper on model system our team designed to study how metabolic stress affects the biology of pancreatic tumors: elifesciences.org/articles/81289. A thread. TLDR: We learned if you grow your cells with the nutrients they would see IRL, they will start behaving like they do IRL.

so there's a species of parasites which doesn't have mitochondria, the *only* known multicellular animal to not have them, which means we don't know how they get their energy from /AND/ they might've evolved from jellyfish cancers that became stable enough to be its own species

RESEARCH BRIEFING The authors determined the metabolome and microbial composition of the liquid luminal content of the gut & the viscous mucus lining the intestinal epithelium at 15 sampling sites along the entire organ in mice. nature.com/articles/s4225…

Online now! Methionine restriction-induced sulfur deficiency impairs antitumour immunity partially through gut microbiota dlvr.it/St8yd0

A family of peptides secreted by the gut helps to keep fungal members of the microbiota under control, according to a new paper in Science Magazine science.org/doi/10.1126/sc…

Congrats to Juan!!! (or should I say Dr. Apiz-Saab, my Muir lab partner in crime)! I know that you'll continue to do incredible science wherever you go and whatever you set your mind to. Always happy to hear all the great news coming from the Muir lab.

Excited and proud to finally see this published!

[emailing my committee at 2:48am] would you guys still let me graduate if I was a worm