Allon Klein Lab
@kleinlabhms
Klein lab @HMS_SysBio. Fate decisions, dev bio, regeneration, single cell genomics, math, data sharing, rubber ducks. Tweets from lab members. Like/RT ≠ endorse
ID: 1171080557456842753
09-09-2019 15:20:02
64 Tweet
2,2K Followers
88 Following
I am really excited to share our latest work on inferring differentiation trajectories by incorporating transcriptome and lineage tracing information, now in Nature Biotechnology. CoSpar performs really well in resolving early fate choices in lineage tracing data. Please try it out!
Congrats Shou-Wen for your next move Westlake University ! Also, please check out the CoSpar video if you are interested!
Interested to learn abt single-cell genomics research in India? Join Sci-ROI: Science & Research Opportunities in India's webinar on prospects and challenges of employing sc-omics in India. July 23rd (Saturday) 10 am to 12:15 pm EDT More info and registration link here: sciroi.net/event/challeng… RT n spread the word 🙏
Very pleased to share work from Kalki Kukreja Katie McCauley with Aron Jaffe studying the plasticity of cell and tissue phenotypes under stimulation of 17 different signaling pathways. How “canalized” is cell differentiation? Can we identify the signals inducing disease states?
It has been great to have shouwen wang in our lab. Huge congratulations for starting his own lab at Westlake University ! Looking forward to more awesome work from your lab!
This is a fabulous collaboration between Allon Klein Lab and shouwen wang, Li Li, and Fernando Camargo. The DARLIN mice is superior to CARLIN, and the single-cell multi-omic lineage tracing method is a great addition to single-cell genomics toolkits!
❔What is special about an immune system that successfully attacks tumors, compared to one that doesn’t? Our new study in Cell led by Jeremy Gungabeesoon, Nico Gort-Freitas and Máté Kiss aimed to address this question. A joint work with the great Allon Klein Lab authors.elsevier.com/a/1gqieL7PXmbtw
Shout out to Nico Gort-Freitas, Jeremy Gungabeesoon, @Mate_Kiss on our paper doi.org/10.1016/j.cell… on heterogeneity in tumor neutrophils and why it matters. A great summary by The Pittet Lab below: