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Please share this broadly. We are excited to continue to expand our community of microbiologists!

#Epigenetic readers are often mutated in disease, but their functions remain largely unknown. @HajeraAmatullah Kate Jeffrey study reader SP140 in #Crohnsdisease and reveal new avenues for CD research. Bonus- another great application of CUTANA™ CUT&Tag! hubs.la/Q01ltrJS0

A great collaboration with Cameron McAlpine and Fil Swirski & Scientists. Lack of #sleep promotes inflammation via #epigenetic alterations in HSPCs

A fantastic discovery by Megha Basavappa (Jeffrey lab alum) and tour-de-force @FlyByVirus. Direct antiviral functions for a lncRNA.

New in Nature Genetics, Karthik Jagadeesh, Kushal K Dey et al present sc-linker— a method to integrate scRNA-seq and GWAS data & identify cell-type specific disease programs! 🎉 Exciting work from the #KlarmanCellObservatory nature.com/articles/s4158…

SP140 regulates #microbiota & IBD risk. Isabella Fraschilla Kate Jeffrey show phagocytes lacking SP140 (#epigenetic reader linked to #CrohnsDisease) are unable to mount homeostatic #antibacterial responses. Pathobionts expand in mice & humans lacking SP140 cell.com/cell-host-micr…

#Viruses contribute to intestinal homeostasis but can also provoke inflammation. Join our webinar to learn how Kate Jeffrey Moderna identifies unique enteric viruses associated with inflammatory diseases. 📆December 1 @ 11AM EST Register now: drugdiscoverynews.com/the-dark-side-…

Counting down the days to 2023! Today we are highlighting the use of CUTANA CUT&Tag by Kate Jeffrey to help understand how variants in the #epigenetic reader protein SP140 impact macrophage function and Crohn's disease. Read more here: hubs.la/Q01wqQX60

Vale, David Allis. #epigenetics #chromatin

ICIS members watch 2022 Annual Business Meeting, win a hoodie ChrisHunter @slg1717 Judi Allen JakStatMan Kate Fitzgerald CarpenterLab Kate Jeffrey Dusan Bogunovic Ruby Dawson Justina Kulikauskaite Vangelis Andreakos cytokinesociety.org/2022-icis-annu… via cytokinesociety.org/2022-icis-annu…

Selected by editor Ifor Williams for #DayOfImmunology, this work offered a way to identify gut viruses that drive illness in patients with #IBD—a growing public health concern in many countries. Nikoo Fatemeh Adili, MD.MPH Kate Jeffrey MGH Division of Gastroenterology scim.ag/2qk

Explore emerging #Macrophage #Neutrophils research with field leaders Keystone Symposia Innate Immunity Across the Molecular, Cellular, Tissue and Therapeutic, this April in Banff! keysym.us/KSInnateImmune… #KSInnateImmune24

Come work with me at Moderna! Our Immune Therapeutics team is seeking a bold, relentless, innovative immunologist and leader at the Executive Director level to discover and deliver on the next wave of mRNA-based immune therapies. #mrna #Immunology modernatx.wd1.myworkdayjobs.com/M_tx/job/Cambr…