Very grateful to AACR and The Breast Cancer Research Foundation for their Career Development Award to fund our research on race-aware multimodal predictors of response to neoadjuvant therapy for breast cancer patients. #AACR24

Grateful for ongoing mentorship from Karuna Ganesh and the opportunity to present early findings from our longitudinal study of #microbiome correlates of early age at onset and tumor sidedness in #CRC Memorial Sloan Kettering Cancer Center University Hospitals Case Comp Cancer Ctr

Appreciate the opportunity to discuss our NEO-RT trial for stage I #rectalcancer . Open now via NCTN NCI CTEP Clinical Research !

CCTG Fight Colorectal Cancer Colon Cancer Foundation OncoAlert Dr. Carl J Brown 🌎 Josh Smith, MD, PhD, FACS Colorectal Cancer Alliance Manju George MVSc PhD Rectal Cancer Survivor Pashtoon Kasi MD, MS Prajnan Das, MD, MS, MPH Fergal Fleming

Support these talented surgeons riding 2 help our patients & support cancer research Cycle for Survival
Drs. Farrow, Foster, Saadat & Liu Memorial Sloan Kettering Cancer Center:
Nellie: secure2.convio.net/mskcc/site/TR/…
Deshka: secure2.convio.net/mskcc/site/TR/…
Lily: secure2.convio.net/mskcc/site/TR/…
Marion: secure2.convio.net/mskcc/site/TR/…

Busy morning at #GI24 poster session w/outstanding SmithLab & GarciaLab members representing Memorial Sloan Kettering Cancer Center @ #GI24 Topics include: accuracy of endoscopy/MRI post-TNT, Local excision/ESD post-TNT, Rectal Cancer Tumoroid Biorepository & brain met genomics from colorectal origin

Thank you to the >80 sites that have opened #ERASur and are actively offering this study to patients. For sites that don’t have it open, please consider opening this study to help clarify the role of metastatic-directed therapy for patients with mCRC.

Peer mentorship, community, and grantsmanship. Aims page reviews virtually every month - open to all colorectal surgeons and trainees. DM for a link!

The second cohort of National Cancer Institute Early-stage Surgeon Scientist Program (ESSP) met on NIH's campus for a successful and impactful symposium! A huge thank you to our experts for joining. NCI Cancer Training NIH Nastaran Zahir, PhD Oliver Bogler Katherine Gallagher Juliet Emamaullee MD PhD Fiemu Nwariaku Lindsay Demblowski

A few days ago Angelita has been awarded the Bigelow medal from the BostonSurgicalSociety. First woman surgeon ever to receive the award. First colorectal surgeon. First Latin-American surgeon. Me? I had the absolute privilege to walk this GIANT towards the podium.

Thrilled to see Dr. Tim Frankel installed as the inaugural Maud T. Lane Professor of Surgical Oncology!

👏 👏 👏

We are excited to announce the Chairs for the 26th World Congress on Gastrointestinal Cancer:
Stephen Lam Chan, MD, of the The Chinese University of Hong Kong; Eileen M. O’Reilly, MD, of Memorial Sloan Kettering Cancer Center in New York City; and Alberto F. Sobrero, MD, of…

Voting is now open for the ASCO Election! I am honored to be included among these leaders as a candidate for the Nominating Committee. Click👇 to learn more about the candidates and to vote! 🗳️ ASCO Dana-Farber News Dana-Farber's Young-Onset Colorectal Cancer Center @DanaFarber

Josh Smith, MD, PhD, FACS Andrea Cercek Rona Yaeger Emmanouil Pappou Paul Romesser Christopher H. Crane Zsofia Stadler

Join expert Memorial Sloan Kettering Cancer Center & international #colorectal surgeons at this year’s #MSKcolorectalCME MSK CME. Day 1 features live robotic surgeries including TME & CME, expert discussions, & a multidisciplinary tumor board on complex cases. Register at bit.ly/colorectal2023

Congratulations...
Saw the update today on CTG...
so many locations across the US for the JANUS trial.

Updated prior posts in 5 groups and was able to create a new one Colon Stars WA trials group.

facebook.com/groups/1871114…

Excited for our study published in Nature Medicine with Emily Harrold Zsofia Stadler and Benoit JC Rousseau showing the limitations of ICB to prevent future cancers in #lynchsydrome . The cover below was done by my amazing wife Samantha Welker Memorial Sloan Kettering Cancer Center nature.com/articles/s4159…

JANUS: Contd..
📌n=312 patients (113 accrued to date)
Enrolling fast🔥
Add'l endpoints?
📌3Y DFS
📌3Y organ preservation
📌5Y OS
📌Adverse Event (AE) profile
📌Among upfront & delayed TME patients, R0 resection rate, pCR rate
#CRCTrialsChat #RectalCancer

JANUS (cont'd)
📌Clinical complete response determined as in OPRA:
📌3-tiered response criteria: DRE, flex sig and MRI

📌If cCR, then recommend WW (ACTIVE SURVEILLANCE!!)
📌If Incomplete response (iCR) then recommend TME
#CRCTrialsChat #RectalCancer OncoAlert #CRCSM

The JANUS Rectal Ca Trial
📌Hypothesis: chemo intensification in context of TNT will⬆️cCR rates in pts w/locally advanced rectal cancer
📌Specifically: cCR rates will be⬆️in pts treated w/ triplet vs. doublet chemo after LCRT
📌Rationale: cCR → organ preservation!
#CRCTrialsChat

Ostomy issues?
📌Wound ostomy care nurse (wocn)excellent resource=>critical for pre, peri- & post-op period
📌Other Pts=>imp resource in pre-op period
📌Counseling for body-image issues
📌For parastomal/perineal hernia=>hernia belts, supportive garments, etc
#CRCTrialsChat