Nice new resource from trevor-lithgow.bsky.social LithgowLab Monash University published today in @NAR_Open: AcrHub: an integrative hub for investigating, predicting and mapping anti-CRISPR proteins. Se more tope papers by Aussie authors at pubswithimpact.herokuapp.com

You’ve heard of the bacterial CRISPR immune system (2020 The Nobel Prize in Chemistry)! What about the phage’s anti-CRISPR response? Check out our AcrHub resource (published in the 2021 NAR database issue) if you want to analyse or predict anti-CRISPR proteins pacrispr.erc.monash.edu/AcrHub/

LithgowLab Jiawei Wang 🏴󠁧󠁢󠁥󠁮󠁧󠁿 Wei Dai trevor-lithgow.bsky.social Christopher Stubenrauch Genome editing tools may advance faster and more safely with anti-CRISPR-CAS knowledge. Exciting for this to be made freely available to the research community: ArcHub pacrispr.erc.monash.edu/AcrHub/

Therapeutic phages can be used as treatments to kill diagnosed #AMR infections. The most valuable ones have good shelf-life properties. We found some doi.org/10.1128/mSyste… trevor-lithgow.bsky.social Phage Directory Monash University @GregHuntMP @AusGov_Superbug Department of Industry, Science and Resources 1/5

We have tapped natural reservoirs with project partners, the Wurrundjeri and Woi Wurrung people (wurundjeri.com.au), the Traditional Owners of the lands on which we work doi.org/10.1128/mSyste… Phage Directory Rhys Dunstan Jiawei Wang 🏴󠁧󠁢󠁥󠁮󠁧󠁿 trevor-lithgow.bsky.social EIC Jack Gilbert 2/5

We needed a reliable way to characterize the structural parts of the phage particle. Our response? We built an artificial intelligence #AI to understand and characterize the new phages doi.org/10.1128/mSyste… EIC Jack Gilbert trevor-lithgow.bsky.social Rhys Dunstan Jiawei Wang 🏴󠁧󠁢󠁥󠁮󠁧󠁿 3/5

While overseas, even the dinosaurs are fully vaccinated …

It’s the standing on the shoulders of giants idea … with everything that the 1952 elite sportsfolk achieved through being at the top of their craft, the 2021 elite sportsfolk are where they are today. Science is an elite sport.

A mentor’s love for their trainees can be measured in tracked changes

Very well deserved...🍭😍

Great teamwork to make this happen : ) 🎯🧩

Great to see this work generated out of our ECR Program...exciting paper on the secretion of proteins by non-classical (and many of them genuinely novel) pathways out of Gram-positive pathogens. Led by Christopher Stubenrauch and Jiawei Wang 🏴󠁧󠁢󠁥󠁮󠁧󠁿 available @ doi: 10.1093/nar/gkab814

When it comes to #AMR, it is clear that resistance genes - like the ones that encode drug pumps - are spread through gene transfer. But these alien genes encode alien proteins…what if these new proteins can’t be assembled? No #AMR. How cool! ⁦1/3 journals.plos.org/plosbiology/ar…

Crosslinking study reveals how chaperone TAM helps Gram-neg #bacteria insert #DrugEffluxPump subunit TolC into their outer membrane (TolC is found in all LPS-containing bugs) Christopher Stubenrauch trevor-lithgow.bsky.social Jiawei Wang 🏴󠁧󠁢󠁥󠁮󠁧󠁿 LithgowLab #PLOSBiology plos.io/3Inyx50

This week I joined MIG🦋@mig-unimelb.bsky.social, BioSciences UniMelb and the Doherty Institute at Melbourne Uni, where I will be leading a group studying the functioning and evolution of microbial networks. If you are interested in the field do get in touch!

"Our new Fellows bring excellence in scholarship combined with passion for their research - which addresses some of the biggest problems facing the world today" - Wolfson President Professor Jane Clarke 🐺 Meet the newest members of Wolfson College's Fellowship wolfson.cam.ac.uk/about/news/nan…

Join us online for our #singlecell RNA-seq analysis course using Python. We'll cover the analysis of single-cell RNA-seq data using Python Software Foundation and command line tools. Run in association with Cambridge Bioinformatics Training & CRUK Cambridge Institute bioinformatics core. Apply by 9 June: ebi.ac.uk/training/event…

A big thank you to everyone involved in this week's joint EMBL-EBI Training and European Hematology Association computational biology training in hematology (CBTH) course. 2025 applications are now open if you want to be in the next cohort of early-career researchers: ehaweb.org/research/resea…

It's been lovely to welcome participants for "Bioinformatics for immunologists" this week. Keep an eye out for the course materials, which will be on our website soon. Interested in #learning more about #bioinformatics? Take a look at our courses: ebi.ac.uk/training/live-…

We're so excited to get back to running our courses that we've had two this week! Thank you to everyone for joining us on "Single-cell RNA-seq analysis with Python Software Foundation " Do you want to join this course in 2025? Submit your application by 17 Nov: ebi.ac.uk/training/event…