Last preprint from Serrano lab, beautiful work by Valentina Ramponi studying the vulnerabilities of persistent cancer cells after therapy and ways to target them all! 💥

Beyond excited to share this exciting work in Nature Cancer :
PD-L2 expressed by #senescent cells as immunotherapy target in combination with chemo!💥
Kudos to all the authors, specially José Alberto López and Selim Chaib!

Iron accumulation as a key factor in senescence and fibrosis 💥🔥 Cool work leaded by Mate Maus The Maus Lab in Nature Metabolism !

Vitamin B12 as a driver of tissue regeneration (and reprogramming). Check out this cool work by Marta Kovatcheva 🥰

And one of my favorite players, CD8 T cells Immunity

Revisiting my favorite cycle. Beautiful Immunity

Lymph node sharing between pancreas, gut, and liver leads to immune crosstalk and regulation of pancreatic autoimmunity dlvr.it/Sw3W9M

Happy to share a link to our recent review of dendritic cells in cancer, written together with the great Mempel Lab Christopher Garris and MauroDiPilato.

Here is a link giving full access to the paper: authors.elsevier.com/a/1hlQ83qNrUu3…

Online now: Tertiary lymphoid structures and B cells: An intratumoral immunity cycle dlvr.it/SvxdQH

Focal RT trigger rapid recruitment and activation of monocytes promoting anti-tumor immunity… while not-so-focal RT affecting healthy tissue hamper this effect. Really cool study in ⁦Science Immunology⁩ 🤩 science.org/doi/10.1126/sc…

Very nice focus summarizing the latest work on #senescent cells as *thermostats* of #antitumor #immunity in Science Translational Medicine 🤩

www-science-org.sire.ub.edu/doi/10.1126/sc…

Super nice work exploring the dynamic immune control of tumors in situ nature 🔥
nature.com/articles/s4158…

Beautiful story on the effect of ICB therapy in glioblastoma and the different responses to different regimes in Nature Cancer 🤩
RT + Adjuvant>>concurrent ICB + Tregs depletion as a promising strategy in this aggressive tumors 💥

nature.com/articles/s4301…

Further evidence on the “danger” of PD-L1 blockade therapy: activation of Tregs, in Science Immunology

science.org/doi/10.1126/sc…

Veeeeeery cool story studying the tolerogenic (vs immunogenic) activation of DCs in Science Immunology

science.org/doi/10.1126/sc…

💎 Beautiful story on how the microbiome influences immunotherapy efficacy by directly modulating PD-L2 expression on DCs, in ⁦nature⁩ !
nature.com/articles/s4158…

Después de 6 meses de trabajo, ayer se celebraron los #premiosvanguardiaciencia de ⁦La Vanguardia⁩ y ⁦@PedreraFundacio⁩. ¡Qué gustazo escuchar a las 4 finalistas y ponerles cara! ⁦⁦@IMIM_research⁩ ⁦Pilar Navarro Lab⁩ ⁦IIBB - CSIC⁩ lavanguardia.com/vida/20230426/…

🏆Neus Martínez (@IMIM_research) y Pilar Navarro Lab (@iibbcsic) reciben el premio #VanguardiadelaCiencia .

👉Ines Marin ( #IRBBarcelona ), en 2a posición, ha descubierto cómo mejorar la eficiencia de la quimioterapia usando células senescentes.

Enhorabuena a todas las…

👉Lee más sobre la relevancia del trabajo de Ines Marin y su relación con el premio #Vanguardiadelaciencia en nuestro #blog !

➡️bit.ly/41JPGQl

#IRBScience #WeAreIRB

🔚Finalitzem l’acte de lliurament del premi  #VanguardiadelaCiencia  La Vanguardia @BigVang donant la nostra enhorabona 👏a les guanyadores i finalistes d’aquesta nova edició 💜!!