🔥The 9th Round of Easy Loan, Earn $40 Reward is in progress❗️ ⏰ Promotion Period: January 15th - Feburary 15th, 2025 👉 Register now and check more details at gate.io/campaigns/358

The Crossroads of Clonal Evolution, Differentiation Hierarchy, and Ontogeny in Leukemia Development: brnw.ch/21wRdSp #AMLsm

super excited to share the newest from my lab: a tool that can securely process RNA-seq reads to quantify gene expression. Huge congrats to the dream team Seungwan, Conor Walker, and Annie! We developed a new gene expression quantification algorithm 1/2 nature.com/articles/s4146…

The Crossroads of Clonal Evolution, Differentiation Hierarchy, and Ontogeny in Leukemia Development pubmed.ncbi.nlm.nih.gov/39652739/ in Blood Cancer Discovery Eirini Papapetrou, MD, PhD Franco Izzo Elvin Wagenblast Christopher Sturgeon Icahn School of Medicine at Mount Sinai #leukemia

Fantastic myeloid malignancy workshop Icahn School of Medicine at Mount Sinai The Tisch Cancer Institute. Many great speakers and stimulating discussion,

Delighted to have our Perturb-multiome paper, led by Jorge Diego Martin-Rufino and #AlexisCaulier from our lab, published today in Science Magazine. Please check out this powerful approach to decipher gene regulatory networks enriched for genetic variation: science.org/doi/10.1126/sc…

CHOIR is now online Nature Genetics! CHOIR is a new clustering method for single-cell data that evaluates whether clusters represent statistically distinct cell populations. CHOIR scales to millions of cells and works with single-/multi-omic data of any type! nature.com/articles/s4158…

Inspiring quote from Adam Grant's Rethinking Podcast today: Adam Grant: "Best life advice?" Daniel Gilbert: "My father... said to me you will think for your entire career that your research is what matters most, but then you will get old and realize it was the students."

Thrilled to share the first pre-print from our lab! We tackled a big question: Why are some pediatric leukemias extremely aggressive? We explored the developmental origins of fusion-driven acute myeloid leukemia (AML). Let's dive in! #AML #NUP98 n/13

So excited to share our new paper out today in nature. We repurposed R2 retrotransposons to create STITCHR, a tool that can make diverse edits in mammalian genomes including scarless multi-kilobase scale insertions nature.com/articles/s4158…

AND👇🏻the link to our recent article in Nature Cell Biology! Treat: 1-We show that human bone marrow hematopoietic stem cells (HSCs) exit quiescence upon myocardial infarction (MI); 2-Our lineage tracing data suggest that HSCs produce pro-inflammatory myeloid.. nature.com/articles/s4155…

What happens when sequencing costs go ⏬ ? Imagination and new opportunities go ⏫ Dan Landau Let's look at what you can do when you perform deep WGS on cfDNA for cancer detection. Our recent work with the Ultima Genomics platform 🧵👇 Lets goooo!! rdcu.be/ehkUb

The integration of duplex sequencing with cost-effective Ultima sequencing enhances the accuracy of whole-genome circulating cell-free DNA profiling. Dan Landau Alexandre Pellan Cheng nature.com/articles/s4159…

A new, error-corrected method for detecting tumor DNA from blood samples is much more sensitive and accurate than prior methods, according to findings from Dr. Dan Landau (Dan Landau) and Dr. Bishoy Faltas (Dr. Bishoy M. Faltas). Full story: bit.ly/3EjLGQ2

I forgot to mention! We're recruiting graduate students to develop the next generation of cancer detection tools. Our lab is ideally located in #Montreal and is affiliated with Centre de recherche du CHUM and École de technologie supérieure ^amazing place to go from innovation ▶️ clinic Apply: tinyurl.com/mwtaesee

From Emily Bernstein Lab and colleagues: The SWI/SNF PBAF complex facilitates REST occupancy at repressive chromatin: Molecular Cell cell.com/molecular-cell… Icahn School of Medicine at Mount Sinai Elena Grossi

🎉 Excited to share the latest work from our lab uncovering an unappreciated role for the SWI/SNF PBAF complex at repressive chromatin🧬 Led by Elena Grossi and now published Molecular Cell cell.com/molecular-cell…

Excited to share with everyone our newest study on precision genome editing – QBEmax base editors! These editors exhibit robust activity but importantly, maximize product purity while minimizing indel formation and off-target editing. 🧬 nature.com/articles/s4158…

Today is #AMLWorldAwarenessDay — a global initiative to raise awareness of acute myeloid leukemia (#AML). Individuals with #RUNX1FPD face a significantly increased risk of developing AML in their lifetime. While efforts continue to advance prevention and intervention strategies,

Excited to announce that we are starting to look for a Lab Manager for our group! Let me know if you are interested in joining!

We are pleased to announce that Dr Ari Melnick has been appointed new Director of the Josep Carreras Leukaemia Research Institute. Dr Melnick will lead IJC in our mission to advance #research in #leukaemia and other malignant blood diseases. Read the full release here: