
Hughes Group
@foldinggenome
Gene regulation | Chromatin folding | Nuclear organization
@MRC_MHU @MRC_WIMM @RDMOxford - managed by @jenniherrmann.
ID: 837320229407584258
http://www.imm.ox.ac.uk/research/research-groups/hughes-group 02-03-2017 15:14:34
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@DaanNoordermeer provides an insightful synthesis to the recent papers by us and the Charles Danko lab on RNAPII contributing to 3D genome folding. Although this settles (I hope) the debate about its contribution, it opens up new Qs to follow — read here: rdcu.be/dgRk4

…both our papers are nicely complemented by the following work by the Marieke Oudelaar lab using Mediator depletion — see below: nature.com/articles/s4159…

#WIMMday is underway at Saïd Business School with KJ Patel CAM-OX traveller welcoming attendees from all across the MRC WIMM and beyond 🌞 Looking forward to a day full of exciting talks, posters and networking 🤝


Vincenzo DAngiolella OxfordOncology Kristijan Ramadan Laboratory Dr Katherine Wood Goriely Lab Anne Goriely Lauren Murphy Beth Psaila Patrick Sahakyan Lab The third talk of the student session is on gene regulation in the cell cycle 🛞, given by Jennifer Herrmann (Hughes Group)



👉 10 more days to go! Opportunity to join our facility for some exciting single cell genomics and spatial transcriptomics work, to support University of Oxford and Oxford Cancer projects!



Working on gene regulation? Want to be my colleague Department of Biochemistry at Oxford University ? Apply here (Associate Professorship in association with Brasenose College): my.corehr.com/pls/uoxrecruit…

👉 Looking for a portable, high-throughput and out-of-the-box pipeline for basic processing and visualisation of your bulk ATAC-seq and ChIP-seq data? Look no further! jove.com/t/65633/catch-… Simone G. Riva Emily Georgiades E. Ravza Gur


Please apply if you are interested to join our team MPI for Multidisciplinary Sciences in Göttingen (Germany) as a PhD student and to study the 3D organisation and regulation of the genome!

Very happy to share the final version of our paper in Nature Genetics, in which we reconstitute chromatin domains and find that nucleosome positioning plays an important role in higher-order folding of chromatin: nature.com/articles/s4158…

NEWS: Four researchers from RDM Oxford, Department of Physiology Anatomy & Genetics (DPAG) and Department of Paediatrics were amongst thirteen University of Oxford finalists at this year’s STEM for BRITAIN event, held on Monday at the Houses of Parliament. Congratulations to Jennifer, Grace, Anna and Chloe! 🎉 medsci.ox.ac.uk/news/oxford-ea…


Great collaboration between the Hughes Group and Watkins labs, reporting the first Gain of Function de novo enhancer causing Mendelian disease (ST Depression Syndrome), defining a multidisciplinary path with ML to solving non-coding clinical genetics. medrxiv.org/content/10.110…

Eric Topol Sek Kathiresan MD Jim Johnson, PhD NEJM Fantastic collaboration with Watkins and Hughes Group labs & a significant amount of functional work needed to help understand the mechanism (de novo creation of a cardiomyocyte enhancer) x.com/jrmmhughes/sta…