What is going to happen to HER-2 immunohistochemistry in the post Enhertu era? If you are an oncologist, do you care about HER-2 IHC score moving forward?
daiichisankyo.us/press-releases…

Delphi Study on PIPAC Published in the EJSO :IMPACT study group , congratulation all and happy and proud to contribute to this with colleagues , Prof. Wouter Willaert Prof. Wim Ceelen Dr. Niki Rashidian Dr. Eduard Callebaut Dr. Martin Hübner Dr. Olivia Sgarbura Dr. Francesca

April Issue: Docetaxel-Based #NeoadjuvantChemotherapy Followed by #EnBlocResection for #EsophagealAdenocarcinoma : A 15-Year Retrospective Analysis from a Regional Upper #GastrointestinalCancer Network James Tankel Lorenzo Ferri MD PhD Centre universitaire de santé McGill

rdcu.be/dFT2O

📝Our new paper on recurrence and survival after resection for iCCA is out!

🔍Check out to see the predictors for worse outcomes and how patients with coexisting liver diseases did compared to without

🖇️ journals.lww.com/eurojgh/abstra…

Advances in bioengineering and organic chemistry have enabled targeting of the previously ‘undruggable’ #KRAS ; our latest review from Eileen M O’Reilly & colleagues discusses the successes, challenges & future of KRAS therapeutics in #cancer
Memorial Sloan Kettering Cancer Center
nature.com/articles/s4159…

Led by Sandra Ryeom from Stand Up To Cancer team: Stool protein mass spectrometry identifies biomarkers for the early detection of diffuse-type gastric cancer aacrjournals.org/cancerpreventi…

Andy Chan David A. Drew Jeeyun Lee MD Jeremy L. Davis MD, FACS AACR Cancer Prevention Research

Here we go - less than 5 weeks to #ASCO24 ASCO
Abstracts dropped last week and here's my list for key #GI #abstracts I can't wait to see!
🌟 #plenary for ESOPEC - will we settle FLOT vs CROSS for #esophCA ?
Congrats to all the presenters 👏
👇my picks for special oral abstract

🔄 Not all TMBs are created equal - Tissue context influences ICB efficacy bit.ly/4aypL2u

While rare, pts with BTC & high TMB may derive more benefit from immunotherapy; MDT re-discussion advised Matthew Robinson AMMF Intrahepatic Cholangiocarcinoma With Extrahepatic Metastasis and High Tumor Mutation Burden: Case of Complete Patho… pubmed.ncbi.nlm.nih.gov/38662981/

The final version of our recommendations to maximise the value of tissue to guide treatment when reporting intrahepatic cholangiocarcinoma have just been published AMMF Cholangiocarcinoma Foundation doi.org/10.1016/j.jhep…...

🍇 Is there a role for adjuvant 💊 chemotherapy in resected invasive IPMN?!

🧑‍🧑‍🧒‍🧒 459 pts / 60% adjuvant chemo / 50% gemcitabine alone

🙈 No benefit for survival / recurrence

🧘‍♀️Careful! No RCT data available yet.. what is your practice ?! 🫵

academic.oup.com/bjs/article-ab…

#HCC #microenvironment #cholangiocarcinoma #immunotherapy #MedEd
💥 Topic: The role of tumor microenvironment in cholangiocarcinoma
👉 Full text: lnkd.in/gaFKes-g
💐Hope this will be an interesting reading!

.⁦ESMO - Eur. Oncology⁩ is launching a monthly virtual journal club. 3 papers discussed during 1h by the best experts. The goal is to update all colleagues about the latest advances wherever they are in the 🌍. First session on May ! Stay connected ! esmo.org/about-esmo-mee…

Clinical and pathological factors associated with survival in patients with pancreatic cancer who receive adjuvant therapy after neoadjuvant therapy: A retrospective multi-institutional analysis ⁦SURGERY Journal⁩ ⁦Jash Datta, MD⁩ ⁦Steven D Wexner MD, PhD⁩ surgjournal.com/article/S0039-…

RMC-5127, a First-in-Class, Orally Bioavailable RAS(ON) G12V-Selective Tri-Complex Inhibitor,
is CNS-Penetrant and Drives Regressions in Intracranially Implanted #KRAS G12V Xenograft Tumors
#AACR24 🎯

Hepatic arterial infusion pump chemotherapy combined with systemic chemotherapy for borderline resectable and unresectable #colorectal liver metastases: phase II feasibility study
➡️doi.org/10.1093/bjs/zn…

Treatment of unresectable or borderline-resectable CRLMs with hepatic

April Issue: AJCC Cancer Staging System Version 9: #AppendicealAdenocarcinoma

rdcu.be/dFMkA

Shishir K. Maithel

This is the #Algorithm we have used during our discussion w/ Sam Klempner for #UpperGI
- Testing for MSI, Her 2, CPS (and soon Cldn18.2) is critical!

#OncTwitter #MedTwtitter #gism #MedEd CancerNetwork® #OncEd

HCC dilemma.

Patient started on 1st line lenvatinib 5 years ago, had CR, now progressing. Do you… reply in poll or comments

Tanios Bekaii-Saab, MD Oncology Brothers Mohamedtaki A. Tejani Dr Joseph McCollom DO

The concept of Total Neoadjuvant Therapy (TNT) is nebulous in its meaning. This review examines TNT’s reported efficacy for pancreatic cancer with an aim towards improving standardization. ja.ma/3WkIcDo