🧬 Tieto geeneistämme karttuu vauhdilla: moni on tehnyt DNA-testin tai luovuttanut näytteensä biopankkiin. 🎧 Tuoreessa Tiedekulma podcastissa puhutaan siitä, miten geenit vaikuttavat terveyteen. Nina Mars Mikko Niemi University of Helsinkimed @helsinkiuni open.spotify.com/episode/5218dx…

Thank you Veera Rajagopal  for a lovely summary and context for our preprint describing a missense variant in VE-PTP (PTPRB) associated with central serous chorioretinopathy, glaucoma, and varicose veins. Great follow-up questions that need to be resolved for therapeutic development.

A new preprint from Mikko Hiltunen's group utilises FinnGen to show that the Finnish TYROBP deletion associates with an increased risk and earlier onset of dementia and Alzheimer’s disease in the monoallelic carriers.

📢New FinnGen research from Reeve et al. 📰Oral and non-oral lichen planus show genetic heterogeneity and differential risk for autoimmune disease and oral #cancer cell.com/ajhg/fulltext/…

Do oral and non-oral lichen planus share the same genetics? Yes (20) and no (7)! Our new paper AJHG using FinnGen reveals genetic heterogeneity between the two, with differential risk for autoimmune diseases and oral cancer cell.com/ajhg/fulltext/…. 1/7

Our core team had a great time at the annual get-together in Helsinki! We kicked things off with some productive teamwork sessions, followed by an inspiring guided tour at the modern art museum Kiasma, and wrapped it all up with a delicious dinner. Thanks to everyone who joined!

GenomiTerveys-hankkeessa biopankit ovat rakentaneet toimintamallin, jolla FinnGenistä ja muista biopankkitutkimuksista palautuvaa tietoa näytteenantajan perinnöllisestä sairastumisriskistä voidaan huomioida terveydenhuollossa. Lue lisää HUS Helsingin yliopistollinen sairaala uutisesta: hus.fi/ajankohtaista/…

A large international research team has uncovered genetic factors that predispose women to a genetic phenomenon where some cells lose one of their two X chromosomes (mLOX). The Nature study by Aoxing Liu et al. included almost 170,000 FinnGen participants. finngen.fi/en/new-insight…

Amazing collaboration FinnGen Estonian Biobank deCODE genetics UK Biobank #DBDScohort #MoBAcohort identified genetics involved in postpartum bleeding- the condition accountable for most maternal deaths globally 🌍 nature.com/articles/s4158…

Uusi FinnGen ja Estonian Biobank julkaisumme polygeenisen riskiarvion käytöstä epilepsian biomarkkerina Our new publication out about polygenic risk scores as biomarker of epilepsy Nature Communications UEF Neuroscience NeurocenterFI nature.com/articles/s4146…

An international research team has developed a proteomics-based age clock for UK Biobank participants and validated its accuracy in the China Kadoorie Biobank and FinnGen. Proteomic aging is associated with mortality, risk of many chronic diseases and numerous age-related traits.

FinnGen has contributed to these interesting new results showing that a protein-based age clock of 204 proteins can accurately predict chronological age and the risk of common age-related diseases: ox.ac.uk/news/2024-08-0…

In a new Nature Medicine study, researchers from CGM at MGH and colleagues developed a proteomic aging clock that predicts mortality and risk of common age-related diseases in diverse populations. Read more: massgeneral.org/news/research-… Austin Argentieri Mark Daly Aarno Palotie FinnGen

Valkosormisuuden eli Raynaud’n taudin taustalta löydettiin kahdeksan immuniteettiin ja verenkiertoon vaikuttavaa geeniä. Helsingin yliopiston johtama tutkimus toteutettiin FinnGen-tutkimusaineistoa sekä muita laajoja geenitutkimusaineistoja hyödyntämällä. finngen.fi/fi/uutta-tutki…

Raynaud's Syndrome Genetics & Biology Uncovered Hanna M Ollila who led the study called it "a prime example of an approach where genetic GWAS-driven discovery is used to study disease pathomechanisms and identify several causal genes related to a disease". genomeweb.com/genetic-resear…

Lisää FinnGen-tuloksia University of Eastern Finland tutkijoilta! Ensimmäinen laaja normaalipaineiseen hydrokefaliaan (NPH) keskittynyt geenitutkimus toi uutta tietoa NPH:n geneettisestä taustasta, antaen pohjan jatkotutkimuksille taudin mekanismien selvittämiseksi. uef.fi/fi/artikkeli/u…