Blood stem cell clones (CHIP), common with aging, associated with higher mortality, promotes inflammation ->
—bone loss, gum disease, arthritis
cell.com/cell/fulltext/… Cell
and
—expand with biologic aging
nature.com/articles/s4358…
Nature Aging

Your face plus deep learning #AI .
A dead giveaway for obstructive coronary artery disease?
informatics.bmj.com/cgi/content/sh…

He's right. Rick Bright on #H5N1
nytimes.com/2024/06/02/opi…
Lack of cow virus sequencing data and lack of serology testing in people keep us in the dark

In Denmark, the use of #AI with mammography screening improved breast cancer detection rate, reduced false positives, reduced callbacks, and reduced radiologist workloads
pubs.rsna.org/doi/epdf/10.11…
Radiology

How assessment of proteins in our blood—proteomic score— is sharpening our ability to predict diseases, beyond polygenic risk scores (PRS)
nature.com/articles/s4159…
Nature Medicine

The ACP published an #AI position paper today
acpjournals.org/doi/full/10.73… Annals of Int Med Nadia Deepti Pandita, MD, FACP, FAMIA Shari Erickson (she/her/hers) and colleagues

Why TREM1, a pro-inflammatory factor, has become an attractive target to potentially slow brain aging and protect vs #Alzheimer 's disease
nature.com/articles/s4159…
Nature Immunology Michael Heneka

The contrast between the therapeutic effect of daytime physiologic light vs metabolic interference of artificial light at night (LAN) nature.com/articles/s4225…
Nature Metabolism review

Our #AI times :-)

'With multimodal #AI , there’s an extraordinary opportunity to do for medicine what GraphCast did for weather forecasting,' writes Eric Topol in a new #ScienceExpertVoices article.

📄: scim.ag/7aS

1/ Can AI diagnose rare diseases better than human experts?

We compared CheXzero (self-supervised AI) vs 227 radiologists on 79 chest X-ray pathologies.

CheXzero significantly outperformed humans, especially on uncommon conditions. Huge implications for improving diagnosis of

From the scientist who coined the term 'Forever Chemicals,' an important oped at The Washington Post

We're familiar w/engineered T cells, known as CAR
Now there's Armored CAR!
eurekalert.org/news-releases/…
“We’ve likened this CAR T to an armored truck or tank because the release of IL 18 further protects the CAR T cells and promotes their ability to attack the cancer

60% vs 8% 5-year progression-free survival (PFS).
A breakthrough for a type of advanced lung cancer.
ascopubs.org/doi/pdf/10.120…
Journal of Clinical Oncology ASCO Ben Solomon

Today the first 3-year follow-up of #LongCovid for outcomes Nature Medicine nature.com/articles/s4159…
Ziyad Al-Aly, MD and I review the findings along w/ several relevant new reports and current status in the new Ground Truths
+ Ziyad's🧵on the new report
x.com/zalaly/status/…