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Our latest: a new optogenetic system for precise spatiotemporal control of gene expression We use it to dissect the dynamics of Shh gradient formation & patterning A thread 🧵 biorxiv.org/content/10.110…

#SynBYSS 10AM USA CT 128th on Jun 13 with Prof Michael Elowitz ElowitzLab & Brendan Camellato New York University 129th on Jun 20 with Prof Chris Myers at CU Boulder CU Boulder 🦬 & Dr Jingchuan Luo at Whitehead Inst. Whitehead Institute Zoom for general audience👇 us02web.zoom.us/j/88380504839

Beautiful work from Brendan Camellato, and a wonderful series -- thanks Tae Teok for creating and sustaining this.

We are searching for an administrative coordinator for the lab here at Caltech. If you know any excellent people interested in supporting a wonderful group synthetic and systems biology researchers, please share! linkedin.com/jobs/view/3948… hhmi.wd1.myworkdayjobs.com/en-US/External…

Really enjoyed Origins, the inaugural issue of Asimov Press! Many thanks to Niko McCarty 🧫 and Xander Balwit for helping to get it across the pond!

Are you a top-tier software engineer looking to solve real problems and accelerate biotech? Our talented and dynamic software team at Plasmidsaurus is pushing SynBio forward and we are looking for fun, super cracked colleagues. Interested? plasmidsaurus.com/static-public/… (please RT)

Alex Schier and I are super happy to share this review for the 50th Cell. We really enjoyed working on it and we hope you will share our excitement for developmental biology: from pattern formation, self organisation and human development! cell.com/cell/abstract/…

Seeking an Administrative Coordinator to support our systems/synthetic bio lab at Caltech/HHMI. Ideal candidates are energetic, organized, good with people, good writers, and excited about biological research. Thanks for sharing with potential candidates hhmi.wd1.myworkdayjobs.com/en-US/External…

If you are among the best in the world at cloning, plasmid prep, viral vector prep, sequencing prep, construct design, genome assembly, etc, please reach out to [email protected] or DM me if interested. We want to hire you.

Check out this awesome work from Will — a huge step towards the dream of multiplexed long-term recording of cellular histories.

Attention prospective postdocs! The Azrieli International Postdoctoral Fellowship for Research at Israeli Universities in STEM, Humanities, and Social Sciences is now open for applications! You can apply today for the 2025–26 cohort. The Azrieli International Postdoctoral

Top 10 Manu Prakash teachings from his amazing episode of the Night Science Podcast. 1. Science is a sense of wonder; a personal sense of experience. 2. Science gives us increasing agency; you realize it’s like a car you drive with no roads. 🧵⬇️ Manu Prakash Martin Lercher

Published today in nature, we describe an approach for single-molecule protein reading on Oxford Nanopore arrays. By utilizing ClpX unfoldase to ratchet proteins through a CsgG nanopore, we achieved single-amino-acid sensitivity. nature.com/articles/s4158…

AI-Science: New features! - Human-AI copilot app: Much more powerful (and fun) than the AI agents doing it all. - Fully annotated figures! - “Data Chaining”: All results (inc Figures) are click-traced to the specific code lines that created them! pip install data-to-paper

Amazing opportunity to work with phenomenal scientist…

The lives of cells, recorded go.nature.com/4g2gRwG #Perspective by Amjad Askary, Wei Chen, Junhong Choi, Lucia Y. Du, ElowitzLab, @james_gagnon, Alex Schier, Sophie Seidel, Jay Shendure, Tanja Stadler & Martin Tran

How could we identify key genes involved in any biological process and cell type? Please read on about Nuclear In-Situ Sequencing (NIS-Seq) nature.com/articles/s4158…

I just love the great writing, beautiful books (and now...the capsule!) that Niko McCarty 🧫 and others at Asimov Press are creating.

Beautiful paper from sandynandagopal , Galit Lahav & colleagues. a seemingly “messy” circuit of dimerizing proteins (bHLH factors) can process a combinatorial input signals. Important step in more systematically understanding biological signal processing