Our comprehensive review of #LongCovid has just been published nature.com/articles/s4157… Phenomenal work by Hannah Davis Lisa McCorkell julia Nature Reviews Microbiology

The Russian regime couldn't be more explicit. The Ukrainians are either a subhuman disease or Russians who don't know it yet. Yet people on the far right and left like Briahna Joy Gray and Elon Musk look at a War of Extermination in Europe and conclude: let them fight. Or worse.

Yale University historian Timothy Snyder says the evidence of Russian genocide in Ukraine is “clear” but argues that many in the West remain reluctant to directly accuse the Kremlin as this would oblige them to act more decisively. businessukraine.ua/timothy-snyder…

My conversation with Bruce Wilkoff, a cardiologist colleague who dedicated his career to preventing sudden death, now finds a gift in death he's facing. A new Ground Truths podcast (link in profile)

This is the detour of the #SARSCoV2 evolutionary arc that I wrote about erictopol.substack.com/p/the-virus-ta…

A very impressive study for #AI picking up pancreatic cancer from non-contrast CT with 93% sensitivity, 99.9% specificity, AUC ~0.99, including from chest CT scans performed Covid. nature.com/articles/s4159… Nature Medicine

"The symbiosis of human and machine intelligence is forging a new epoch of cultural evolution."—#GPT4 Yes, we've entered the "machine culture," a culture mediated or generated by machines. A very thoughtful perspective free access rdcu.be/drzoS Iyad Rahwan | إياد رهوان

Here's the full video link of our conversation youtu.be/YLY1oEnvnRA

An exceptional review of how obesity revs up the immune system and inflammation, including what happens with weight regain science.org/doi/10.1126/sc… Science Translational Medicine Alyssa Hasty Vanderbilt Health

In case you thought the background science and path for development of GLP-1 drugs to tackle obesity was quick and easy! science.org/doi/10.1126/sc… Science Translational Medicine Matthias Tschöp

Eric Topol Science Translational Medicine Matthias Tschöp Absolutely, the journey to develop GLP-1 drugs for obesity underscores the complexity of medical research and drug development. Each innovation is the result of years, if not decades, of foundational science, trials, and collaborative effort. For those looking to delve deeper

3 New #LongCovid reports 1. Vaccination protection—1 dose 21%, 2 doses 59%, 3 doses 73% among ~590,000 people in Sweden (strong association) bmj.com/content/383/bm…

Two amazing leaders in their respective fields, before hitting your pillow tonight, make some time to learn and grow. Eric Topol Andrew Ng #AI #AIinHealthcare OpenAI

No.

Not beat or cure by itself. But many important ways that #AI will help advance prevention and treatment, as previously reviewed erictopol.substack.com/p/a-one-two-pu… erictopol.substack.com/p/how-to-upend…

Evidence for the high level of protection of the XBB.1.5 ("updated") Covid vaccine vs current circulating variants from the Netherlands in advanced age groups 71% protection vs hospitalization 73% protection vs ICU admission medrxiv.org/content/10.110…

Robust mucosal immunity vs Covid, which can achieved by an inhalation vaccine (IT below), in non-human primates, provided near complete protection for blocking infections, greatly exceeding that of shots. nature.com/articles/s4158… Barouch Lab

I don't *necessarily* think this spike will be the case for the US. But it remains possible. These spikes seen after Pirola dominance in these various countries is somewhat eye opening, we will need to watch the trends in more places I hope to not have to update the forecast

An upbeat view of US life expectancy "Children born this year will live longer than in any previous year" wsj.com/health/healthc…

There's plenty going on in the world of Covid. Here's an update that includes the JN.1 variant, US status, the booster, #LongCovid, new inhalation vaccine data, and my bout. In a new Ground Truths (see profile)