Dr Mark Lythgoe (@drmarklythgoe) 's Twitter Profile
Dr Mark Lythgoe

@drmarklythgoe

Medical Oncology fellow & Pharmacist at @imperialcollege @ImperialSandC doing PhD in #cancer #microbiome -interest in health policy, drug development & @rovers

ID: 1076844095606325249

calendar_today23-12-2018 14:16:53

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Dr Mark Lythgoe (@drmarklythgoe) 's Twitter Profile Photo

Not all PDL1 assays are the same in #bladder #cancer - important work. do we need to re-evaluate the clinical utility of how we measure PDL1 and does this have implications for other cancers??? David J. Benjamin, MD Tom Powles Dr Amol Akhade Fight Bladder Cancer aacrjournals.org/cancerimmunolr…

Bishal Gyawali, MD, PhD, FASCO (@oncology_bg) 's Twitter Profile Photo

Brand new paper just live in BMJ Oncology . In this study, we evaluate if DFS can be a reliable surrogate for OS in early-stage pancreatic cancer trials. I hope trial sponsors and trialists will find these results helpful and meaningful. Link in next comment. Special shout out to

Brand new paper just live in <a href="/BMJOncology/">BMJ Oncology</a> . In this study, we evaluate if DFS can be a reliable surrogate for OS in early-stage pancreatic cancer trials. I hope trial sponsors and trialists will find these results helpful and meaningful. Link in next comment.
Special shout out to
Kristina Jenei (@kjmeetswrld) 's Twitter Profile Photo

Several malignancies for which there are no medicines recommended on the EML, including stomach, liver, esophagus, thyroid, bladder, pancreas, kidney, uteri, gallbladder, vulva, penis, mesothelioma, and vaginal cancers (30% of cancer cases globally) academic.oup.com/jnci/article/d…

Kristina Jenei (@kjmeetswrld) 's Twitter Profile Photo

💡New in JCP with Ariadna Tibau Martorell Aaron Kesselheim We find the time for U.S. FDA oncology indications to achieve conversion to regular approval or be withdrawn has shortened. Also, prop of confirmatory studies underway at the time of approval has increased. sciencedirect.com/science/articl…

💡New in JCP with <a href="/ariadna_tibau/">Ariadna Tibau Martorell</a> <a href="/akesselheim/">Aaron Kesselheim</a> 

We find the time for <a href="/US_FDA/">U.S. FDA</a> oncology indications to achieve conversion to regular approval or be withdrawn has shortened. Also, prop of  confirmatory studies underway at the time of approval has increased. 
sciencedirect.com/science/articl…
David J. Benjamin, MD (@davidbenjaminmd) 's Twitter Profile Photo

Thank you Cancer Today AACR for featuring our recent ESMO - Eur. Oncology Real World Data & Digital Oncology study on the portrayal of cancer in public figures in news stories. The public should be cognizant that many news articles lack pertinent details on an individual's diagnosis,

Dr Mark Lythgoe (@drmarklythgoe) 's Twitter Profile Photo

Simple things work best in #clinical #trial recruitment - single page recruitment letter………….though no preference in different colours! Ash Paul ECMC Network (@ecmc-uk.bsky.social) Sarah Blagden jamanetwork.com/journals/jama/…

Aakash Desai, MD, MPH, FASCO (@adesaimd) 's Twitter Profile Photo

🚨Our RWE #perioperative #NSCLC study now in JAMA Network Open study of 1334 pts with stage II–IIIA resectable NSCLC: ◼️Neoadj DMFS @ 18 mo: 80% ◼️Adj DMFS @ 18 mo: 83 % ◼️Uptake was low: <30% ◼️Favorable outcomes, but time to expand access OncoAlert bit.ly/3I5Aeck

🚨Our RWE #perioperative #NSCLC study now in <a href="/JAMANetworkOpen/">JAMA Network Open</a> study of 1334 pts with stage II–IIIA resectable NSCLC:
◼️Neoadj DMFS @ 18 mo: 80%
◼️Adj DMFS @ 18 mo: 83 %
◼️Uptake was low: &lt;30% 
◼️Favorable outcomes, but time to expand access <a href="/OncoAlert/">OncoAlert</a> bit.ly/3I5Aeck
Fotopoulou/Cunnea Ovarian Cancer Research group (@cf_pc_ovcagroup) 's Twitter Profile Photo

Massive congratulations our fantastic Clinical Research Fellow Dr James Clark on passing his PhD viva this afternoon!!! 🎉🎉🎉 Huge thank you to his lovely examiners Professors Gourley and Aboagye for an excellent discussion! Surgery and Cancer Imperial College London

Massive congratulations our fantastic Clinical Research Fellow Dr James Clark on passing his PhD viva this afternoon!!! 🎉🎉🎉 Huge thank you to his lovely examiners Professors Gourley and Aboagye for an excellent discussion! <a href="/ImperialSandC/">Surgery and Cancer</a> <a href="/imperialcollege/">Imperial College London</a>
Lars G. Hemkens (@lghemkens) 's Twitter Profile Photo

>100000 single-arm trials exist. Most use convenience samples & give weak non-generalizable evidence. We can do better. We propose Random Invitation Single-Arm Trials (RISAT) - a simple way to get randomized real-world evidence from SATs. Annals of Int Med acpjournals.org/doi/10.7326/AN…

Dr Mark Lythgoe (@drmarklythgoe) 's Twitter Profile Photo

#UK healthcare research is in serious decline in latest @nature rankings No institution in top 50 #globally or even top 25 in #Europe………….links to decline of #physican #Scientists nature.com/nature-index/r… Cancer Research UK Policy UK Research and Innovation Richard Sullivan The BMJ Andrew Gregory