Great to see the report from Teenage Cancer Trust on the issues facing teenagers & young adults accessing trials & the importance of trial awareness through the ECMC TrialFinder tool.

Join today's webinar at 3pm on considering this community in trials: events.teams.microsoft.com/event/267e84be… #TYACAM

Reminder that if you would like to join the JING steering committee the deadline for applying is Tuesday 30 April

Hear from Juanita (The ICR/The Royal Marsden NHS Foundation Trust ECMC) at the Science and Innovation at Cancer Research UK's upcoming #CRUKBrain24 in September⬇️

Congratulations to Birmingham paediatric ECMC's Pam Kearns on winning Children’s Cancer and Leukaemia Group's Lifetime Achievement Award! Pam has made a huge contribution to the field through her leadership & dedication to children's & young people's cancers. We're proud to have her as part of the network.

This vital biobanking resource for researchers is helping to advance their knowledge of children’s & young people’s cancers. Deborah Tweddle at Sir Bobby Robson Cancer Trials Research Centre is the Director of VIVO Biobank and is dedicated to advancing the way these cancers are treated. 👇 #TYACAM

So happy to finally share! Amazing project and amazing team behind this! Here's to the next steps - translating it into the clinic to really help patients get a quicker diagnosis. World CUP Awareness CUP Foundation CRUK National Biomarker Centre Natalie Cook 💙 NIHR Manchester Biomedical Research Centre nature.com/articles/s4146…

🗣️Call 4 new members of the ECMC Network Research Nurse steering committee. Great opportunity 2 help shape Research Nurse education and research across the adult and paediatric ECMCs. 4 further details rb.gy/6fxnk9 or DM 🙂

Did you hear? We're hosting a webinar on teenager & young adult #Cancer , sharing experience & expertise to overcome the unique challenges facing this age group, including access to #ClinicalTrials & trial design.

📅 30 April
⏰ 3 – 4pm

Sign up: events.teams.microsoft.com/event/267e84be… #TYACAM

Join Dan Stark (Leeds ECMC) & Gillian Horne (Glasgow ECMC) for a webinar dedicated to teenager & young adult cancer on 30 April @ 3pm.

Hear about exemplary projects addressing the challenges facing this age group & from a patient's perspective👉events.teams.microsoft.com/event/267e84be… #TYACAM

It's been brilliant hearing all of the research happening around the world at #AACR24 ! We hope you've enjoyed following along & keep an eye out for more news & opportunities from us 👀

New frontiers in exploiting stroma for therapy. FAP directed precision medicine. Phase I of AVA600 showing tolerability, plasmas/tumour PK and clinical proof of concept response in FAP high tumours. Abstract CT188 #AACR2024 The ICR The Royal Marsden NHS Foundation Trust ECMC Network

In a session on novel agents & emerging therapeutic strategies at #AACR24 , Jonathan Yang (Memorial Sloan Kettering Cancer Center) presents data on the safety & efficacy of AZD1390 + radiation therapy for #Glioblastoma , co-authored by Anthony Chalmers 💙 (@UofGlasgow): bit.ly/3Pxjony

UofG MVLS

At today's clinical trials mini symposium at #AACR24 , data from the iMATRIX Alectinib Phase I/II trial is being presented, investigating Alectinib in children & adolescents, co-authored by Darren Hargrave (UCL/Great Ormond Street Hospital for Children ECMC) 👉 bit.ly/4a2syR7

Roche

Head over to the clinical trials poster session at #AACR24 to hear Markus Muller (Boehringer Ingelheim) presenting data a PII trial of DLL3-targeting T-cell engager in relapsed #SCLC / neuroendocrine carcinomas, co-authored by Alastair Greystoke (@Newcastle_ECMC) 👉 bit.ly/3TLpALj

In section 9 at #AACR24 , data from ITCC-P4 – a preclinical proof-of-concept drug testing platform as a tool for pharmacological screening in pediatric tumour models is being presented, co-authored by Louis Chesler from The ICR paediatric ECMC 👉 bit.ly/4a3YRzm

Hear from udaibanerji (@ICR_London/The Royal Marsden NHS Foundation Trust ECMC co-lead) in the poster session at #AACR24 now, presenting data from the study of acoustic cluster therapy with chemotherapy & insonation in colorectal cancer patients. Head over to section 36. 👉 bit.ly/4cuu8wM

Hear from Alison Dickson (University of St Andrews) presenting data at #AACR24 on factors in the #TME that contribute to tumorigenesis + therapeutic response. Check out poster #6222/25, co-authored by Ruth, Sarah Blagden, Stefan Symeonides & Natalie Cook 💙: bit.ly/3TWW0Tn

.The ICR & The Royal Marsden NHS Foundation Trust ECMC co-lead udaibanerji is presenting a poster, co-authored by Ruth, Natalie Cook 💙 & Jeff Evans on PI trial investigating FAP-released & TME-targeting doxorubicin peptide drug conjugate in FAP-positive #SolidTumors : bit.ly/495xIL4

Messing with (cancer cell) stress. PK-PD and toxicity of the dose escalation cohort of NXP800 (NCT05226507) Abst CT111 at #AACR2024 . Target engagement confirmed, next steps to evaluate efficacy in ARID1A mutated tumours. The ICR The Royal Melbourne Hospital ECMC Network NIHR Royal Marsden BRC with @ICRLondon and CRF