DPCG (@dpcg_official) 's Twitter Profile
DPCG

@dpcg_official

De DPCG is de landelijke multidisciplinaire werkgroep op het gebied van alvleesklierkanker

ID: 3040456673

linkhttp://www.dpcg.nl calendar_today16-02-2015 10:01:48

226 Tweet

774 Followers

282 Following

Simone Augustinus (@simone_aug) 's Twitter Profile Photo

Last call ‼️ Closing 1st May 😱 Are differences in ASA score in HPB surgery actually related to patient factors? Complete MILESTONE-2 survey: uva.fra1.qualtrics.com/jfe/form/SV_1y… Already > 1200 responses, from over 53 countries! 🌍

Last call ‼️ Closing 1st May 😱

Are differences in ASA score in HPB surgery actually related to patient factors? 

Complete MILESTONE-2 survey: uva.fra1.qualtrics.com/jfe/form/SV_1y…

Already > 1200 responses, from over 53 countries! 🌍
Marc Besselink (@marcbesselink) 's Twitter Profile Photo

🧡Team🇳🇱 DPCG and DutchPancreatitisSG at The Pancreas Club #PancreasClub2023 #Chicago presenting our nationwide collaborative research in #PancreaticCancer #Pancreatitis #Surgery Excellent meeting with lenghty discussions…and our slightly hidden supporter: E-AHPBA president

🧡Team🇳🇱 <a href="/DPCG_official/">DPCG</a> and <a href="/pancreatitis_nl/">DutchPancreatitisSG</a> at <a href="/PancreasClub/">The Pancreas Club</a> #PancreasClub2023 #Chicago presenting our nationwide collaborative research in #PancreaticCancer #Pancreatitis #Surgery

Excellent meeting with lenghty discussions…and our slightly hidden supporter: <a href="/EAHPBA/">E-AHPBA</a> president
Marc Besselink (@marcbesselink) 's Twitter Profile Photo

Harmonizing the USA 🇺🇸 and European🇪🇺 composite markers of #Pancreas #Surgery into one 🌎 global “#Ideal #Outcome”: allows comparison of surgical outcomes Simone Augustinus presenting a #GAPASURG project combining data from the registries from: 🇺🇸 🇳🇱 🇩🇪 🇸🇪 europeansurgicalassociation.org/congress

Harmonizing the USA 🇺🇸 and European🇪🇺 composite markers of #Pancreas #Surgery into one 🌎 global “#Ideal #Outcome”: allows comparison of surgical outcomes

<a href="/Simone_Aug/">Simone Augustinus</a> presenting a #GAPASURG project combining data from the registries from: 🇺🇸 🇳🇱 🇩🇪 🇸🇪 
europeansurgicalassociation.org/congress
CycLyon: ride for pancreatic research (@cyclyon2023) 's Twitter Profile Photo

CycLyon 2023: from June 1st to June 6th, a dedicated team of medical researchers will cycle from Brescia to Lyon, to raise funds for pancreatic cancer research. We invite you to follow our journey and support us on Instagram, Facebook, Twitter, and LinkedIn! 🚴‍♂️

CycLyon 2023: from June 1st to June 6th, a dedicated team of medical researchers will cycle from Brescia to Lyon, to raise funds for pancreatic cancer research. We invite you to follow our journey and support us on Instagram, Facebook, Twitter, and LinkedIn! 🚴‍♂️
BJS Open (@bjsopen) 's Twitter Profile Photo

📜by the 🇳🇱 Panc Study group: Network treatment (centralized surgery in expert🏥, adjuvant chemo in local🏥) after panc🔪did not influence time to/completition chemo nor survival! doi.org/10.1093/bjsope… DPCG DutchPancreatitisSG The Pancreas Club #some4hpb #SoMe4Surgery

📜by the 🇳🇱 Panc Study group: Network treatment (centralized surgery in expert🏥, adjuvant chemo in local🏥) after panc🔪did not influence time to/completition chemo nor survival! doi.org/10.1093/bjsope… <a href="/DPCG_official/">DPCG</a> <a href="/pancreatitis_nl/">DutchPancreatitisSG</a> <a href="/PancreasClub/">The Pancreas Club</a> #some4hpb #SoMe4Surgery
AnnalsSurgOncology (@annsurgoncol) 's Twitter Profile Photo

#IntraoperativeUltrasound During #SurgicalExploration in Patients with #PancreaticCancer and Vascular Involvement ( #ULTRAPANC ): A Prospective Multicenter Study rdcu.be/dcTOz #VisualAbstract

#IntraoperativeUltrasound During #SurgicalExploration in Patients with #PancreaticCancer and Vascular Involvement ( #ULTRAPANC ): A Prospective Multicenter Study rdcu.be/dcTOz #VisualAbstract
PHAIR Consortium (@phairconsortium) 's Twitter Profile Photo

📢 Exciting news! The PHAIR Consortium is officially launching today! 🎉 Launch + excellent presentations by: Lois Daamen, Giuseppe Malleo, Åsmund A. Fretland, Ammar Asrar Javed, MD 🇺🇸, and Jackie Bereska. PHAIR aims to drive AI advancements for patients with pancreaticobiliary and hepatic diseases.

📢 Exciting news! The <a href="/PHAIRconsortium/">PHAIR Consortium</a> is officially launching today! 🎉

Launch + excellent presentations by: <a href="/LoisDaamen/">Lois Daamen</a>, <a href="/gimalleo/">Giuseppe Malleo</a>, <a href="/AAFretland/">Åsmund A. Fretland</a>, <a href="/ammar_asrar/">Ammar Asrar Javed, MD 🇺🇸</a>, and Jackie Bereska.

PHAIR aims to drive AI advancements for patients with pancreaticobiliary and hepatic diseases.
Simone Augustinus (@simone_aug) 's Twitter Profile Photo

🚴🏻‍♀️ Help support the CycLyon: ride for pancreatic research team! 🇫🇷 Cycling 650 km from Brescia to E-AHPBA Lyon 🎶 Please add a song to the support playlist: open.spotify.com/playlist/22WnT…

🚴🏻‍♀️ Help support the <a href="/CycLyon2023/">CycLyon: ride for pancreatic research</a> team!

🇫🇷 Cycling 650 km from Brescia to <a href="/EAHPBA/">E-AHPBA</a> Lyon 

🎶 Please add a song to the support playlist: 
open.spotify.com/playlist/22WnT…
Marc Besselink (@marcbesselink) 's Twitter Profile Photo

What are the learning curves for 🤖 #Robotic #Pancreatoduodenectomy in trained “2nd generation” centers? 635 RPDs performed by teams of 17 surgeons in 7 🇳🇱 DPCG centers. All trained in LAELAPS-3 by Melissa Hogg Herbert Zeh Amer Zureikat Conversion rate 6.6%,

What are the learning curves for 🤖 
#Robotic #Pancreatoduodenectomy in trained “2nd generation” centers?

635 RPDs performed by teams of 17 surgeons in 7 🇳🇱 <a href="/DPCG_official/">DPCG</a> centers. All trained in LAELAPS-3 by <a href="/HoggNDMD/">Melissa Hogg</a> <a href="/herbert_zeh/">Herbert Zeh</a> <a href="/AmerZureikatMD/">Amer Zureikat</a> 

Conversion rate 6.6%,
Marc Besselink (@marcbesselink) 's Twitter Profile Photo

Amazing 30+ year old tradition celebrating #Surgical #TeamSpirit: yesterday, #Chirurgencup 🇳🇱(#SurgeonsCup) day between all 7 training regions for #GeneralSurgery 700+ #surgeons, #residents, #PhDstudents incl 2 Amsterdam UMC region teams playing ⚽️🏑🏐🤽‍♂️🎾♣️ and more incl a live

Amazing 30+ year old tradition celebrating #Surgical #TeamSpirit: yesterday, #Chirurgencup 🇳🇱(#SurgeonsCup) day between all 7 training regions for #GeneralSurgery 700+ #surgeons, #residents, #PhDstudents incl 2 <a href="/amsterdamumc/">Amsterdam UMC</a> region teams playing ⚽️🏑🏐🤽‍♂️🎾♣️ and more incl a live
PHAIR Consortium (@phairconsortium) 's Twitter Profile Photo

EPC-Europ Pancr Club #EPC2023 Boris Janssen on behalf of PHAIR Consortium! AI residual cancer burden (RCB) to evaluate impact of NAT in resected pancreatic cancer! RCB 🔬 NAT vs. upfront: 2.2 vs. 10.3 mm2 p<0.0001 Survival 📈 Above vs. below median RCB: 24 vs. 30 months. p=0.018

<a href="/EurPancClub/">EPC-Europ Pancr Club</a> #EPC2023

<a href="/BorisJanssen/">Boris Janssen</a> on behalf of <a href="/PHAIRconsortium/">PHAIR Consortium</a>! 

AI residual cancer burden (RCB) to evaluate impact of NAT in resected pancreatic cancer! 

RCB 🔬
NAT vs. upfront: 2.2 vs. 10.3 mm2
p&lt;0.0001

Survival 📈
Above vs. below median RCB: 24 vs. 30 months. 
p=0.018
Marc Besselink (@marcbesselink) 's Twitter Profile Photo

Should #neoadjuvant #chemorad only be offered in #PancreaticCancer pts with high CA19.9? Probably not! Joint analysis #PREOPANC 🇳🇱 and #Jang 🇰🇷 multicenter trials: ✅ 127pts low CA19-9 <500: mOS 23.5 vs 16.3 mo (HR 0.63, 0.42 to 0.93) ❌ 52pts high CA19-9 >500: mOS 15.5 vs

Should #neoadjuvant #chemorad only be offered in #PancreaticCancer pts with high CA19.9?

Probably not! Joint analysis #PREOPANC 🇳🇱 and #Jang 🇰🇷 multicenter trials:

✅ 127pts low CA19-9 &lt;500:  mOS 23.5 vs 16.3 mo (HR 0.63, 0.42 to 0.93) 

❌ 52pts high CA19-9 &gt;500: mOS 15.5 vs
Marc Besselink (@marcbesselink) 's Twitter Profile Photo

Congrats #DeesjeDoppenberg on a wonderful #PhD on SBRT radiotherapy and surgery in localized #PancreaticCancer Interested? #Thesis ➡️dare.uva.nl/search?identif… 7 studies, 75 co-authors incl #PANCOSAR RCT and #ULTRAPANC study. Thanks to anna bruynzeel DPCG and #TAPS

Congrats #DeesjeDoppenberg on a wonderful #PhD on SBRT radiotherapy and surgery in localized #PancreaticCancer

Interested? #Thesis ➡️dare.uva.nl/search?identif…  7 studies, 75 co-authors incl #PANCOSAR RCT and #ULTRAPANC study. 

Thanks to <a href="/AnnA25_03/">anna bruynzeel</a> <a href="/DPCG_official/">DPCG</a> and #TAPS
Marc Besselink (@marcbesselink) 's Twitter Profile Photo

Study protocol #ENDURO multicenter RCT DPCG: EUS- vs surgical gastro-jejunostomy in patients with malignant gastric outlet obstruction. @FrankVleggaar ➡️Inclusion is on schedule trialsjournal.biomedcentral.com/articles/10.11… #PancreaticCancer #alvleesklierkanker

Study protocol #ENDURO multicenter RCT <a href="/DPCG_official/">DPCG</a>: EUS- vs surgical gastro-jejunostomy in patients with malignant gastric outlet obstruction. @FrankVleggaar

➡️Inclusion is on schedule

trialsjournal.biomedcentral.com/articles/10.11…

#PancreaticCancer #alvleesklierkanker
Simone Augustinus (@simone_aug) 's Twitter Profile Photo

New study by DPCG: TIMEPAN trial ⏰ Asymptomatic metastatic PDAC: ▶️Immediate start chemotherapy ⏸️Start when symptoms occur Primary outcome: quality adjusted survival 👩🏼‍⚕️ ➡️Full protocol: pubmed.ncbi.nlm.nih.gov/37897803/

New study by <a href="/DPCG_official/">DPCG</a>: TIMEPAN trial ⏰

Asymptomatic metastatic PDAC:  
▶️Immediate start chemotherapy
⏸️Start when symptoms occur 

Primary outcome: quality adjusted survival 👩🏼‍⚕️

➡️Full protocol: pubmed.ncbi.nlm.nih.gov/37897803/
Simone Augustinus (@simone_aug) 's Twitter Profile Photo

Timing of initiation of chemotherapy in asymptomatic metastatic PDAC? 1⃣ Expert opinion: 67% prefer immediate start of chemo 2⃣ Meta-analysis: limited evidence available - no survival difference, potential QOL benefit delayed start of chemo 3⃣ Protocol: let's wait and see! 🙏

Timing of initiation of chemotherapy in asymptomatic metastatic PDAC? 

1⃣ Expert opinion: 67% prefer immediate start of chemo
2⃣ Meta-analysis: limited evidence available - no survival difference, potential QOL benefit delayed start of chemo
3⃣ Protocol: let's wait and see! 🙏
Deltaplan Alvleesklierkanker (@deltaplana) 's Twitter Profile Photo

Heb je het al gehoord? Op 13 april gaan we fietsen in de Drunense Duinen in Noord-Brabant. Een kans om een sportieve fietstocht te combineren met steun voor het Deltaplan Alvleesklierkanker. We rijden ANWB-fietsroutes van 50, 80 en 130 km …nt.voordeltaplanalvleesklierkanker.nl

Heb je het al gehoord? Op 13 april gaan we fietsen in de Drunense Duinen in Noord-Brabant. Een kans om een sportieve fietstocht te combineren met steun voor het Deltaplan Alvleesklierkanker. We rijden ANWB-fietsroutes van 50, 80 en 130 km …nt.voordeltaplanalvleesklierkanker.nl
Simone Augustinus (@simone_aug) 's Twitter Profile Photo

Very honored to give the YOUPPIE Pancreas award 🏆presentation at #EPC2024: looking beyond trial results in pancreatic research ⭐️ Key points: 1️⃣ Improve international comparison 2️⃣ Use of alternative RCT designs 3️⃣ Importance of implementation DPCG

Very honored to give the <a href="/YouppiePancreas/">YOUPPIE Pancreas</a> award 🏆presentation at #EPC2024: looking beyond trial results in pancreatic research ⭐️ 

Key points: 
1️⃣ Improve international comparison
2️⃣ Use of alternative RCT designs 
3️⃣ Importance of implementation 

<a href="/DPCG_official/">DPCG</a>
Simone Augustinus (@simone_aug) 's Twitter Profile Photo

💡LIDOPAN study: multicenter pilot trial 💉 IV lidocaine for patients in pain with PDAC and CP 👥30 patients, NRS >4 📈 No overall clinically relevant pain reduction day 1 🤩 31% positive effect, lasted op to a month ncbi.nlm.nih.gov/pubmed/39163321 ACG_CTG

💡LIDOPAN study: multicenter pilot trial

💉 IV lidocaine for patients in pain with PDAC and CP 
👥30 patients, NRS &gt;4 

📈 No overall clinically relevant pain reduction day 1 
🤩 31% positive effect, lasted op to a month

ncbi.nlm.nih.gov/pubmed/39163321

<a href="/ACG_CTG/">ACG_CTG</a>