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Adaptive loss of tRNA gene expression leads to phage resistance in a marine Synechococcus cyanobacterium nature.com/articles/s4156…

Dynamic transitions of initiator binding coordinate the replication of the two chromosomes in Vibrio cholerae 🦠 💫 👏 Marie-Eve Val Théophile Niault Didier Mazel nature.com/articles/s4146…

Ribosomal A-site interactions with near-cognate tRNAs drive stop codon readthrough nature.com/articles/s4159…

@zeynepbaharoglu.bsky.social

Genomic resistance in historical clinical isolates increased in frequency and mobility after the age of antibiotics biorxiv.org/content/10.110…

High-throughput method characterizes hundreds of previously unknown antibiotic resistance mutations #rnasky #microsky #AMR among which ile synonymous codons and tRNA cysteine 🦠 ✨ (ps: find me there => @zeynepbaharoglu.bsky.social) nature.com/articles/s4146…

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Multiple Postdoc and PhD positions in synthetic biology and infection biology nature.com/naturecareers/…

Reminder :)

find me there => @zeynepbaharoglu.bsky.social 🦠💫 I'll continue posting about bacteria, stress, RNAs, antibiotics, ...

🎓 Offre de thèse 👇: Futur(e) doctorant(e) avec un solide background et une appétence pour la bactériologie, la génétique bactérienne et la biologie moléculaire 🧬: Caractérisation d'un nouveau système de défense impliqué dans l'immunité bactérienne 🦠. Deadline 25 Avril

Hosting oppotunity in my lab MSCA Post-doctoral Fellowship at IBPC Paris on RNA modifications in bacteria (FRANCE) 🦠💫 RT euraxess.ec.europa.eu/jobs/hosting/m…

Our May 2025 Newsletter featuring Zeynep Baharoglu @zeynepbaharoglu.bsky.social Dr. Zeynep Baharoglu is Research Director at the CNRS Institut de Biologie Physico-Chimique and the Institut Pasteur in Paris. Subscribe to our newsletter to learn more about the experts.

RNase L cleaves most tRNAs in the anticodon loops into various tRNA-derived RNAs (tDRs) including 5'-tDRAla that shows a translation inhibitory effect. Some tRNAs are also cleaved in variable loops. bit.ly/3YTwlNq

Organoid model showing a role for tRNA modifications and codon usage in Shigella infection 🦠💫 nature.com/articles/s4158…

Detection of stress-dependent m5C rRNA dynamics in E. coli using m5C-Rol-LAMP: qPCR-based method to quantify site-specific m5C in total bacterial RNA =>stress (heat, stressox) dependent changes in rRNA, from Kirsten Jung lab 🦠 #RNAmodifications biorxiv.org/content/10.110…