The final song of the Gala Dinner ceilidh! Auld Lang Syne - traditionally played at Hogmanay (New Year's Eve) - also captures the spirit of the meeting. Induced proximity at its' very finest! 🙏🤣 Thanks for sharing Niko Klink ! #TPDFocus

An inspiring discussion today at the Dana-Farber’s Helen Gurley Brown Presidential Summit with four fantastic scientists and leaders Laurie Glimcher MD, Alexa Kimball, Jean King, and Fiona Marshall. Great community and valuable lessons in how we can pull each other up! #womeninSTEM

Tune in to the @danafarber #TPD webinar this Thursday to listen to two great talks: Elisia Villemure from Genentech presenting a molecular glue degrader working via FBXO22 and Kyle Seamon from Revolution Medicines talking about gluing #KRas 👉Join us bit.ly/3OmMRjp

Recently finished your PhD? Why not spend the next few weeks writing it up into a short, accessible essay? Who knows, it could be published in Science Magazine and get you invited to participate in the The Nobel Prize festivities! Due July 15th - give it a try! 😊 Science & SciLifeLab Prize

Exciting double #polymerisation seminars this week! Join us on Thursday, July 25th at 11 am EDT to hear the duo of Jiho Park and Paul Park from Dana-Farber as well as Marcin J. Suskiewicz from CNRS 🌍 talk about homomerising transcription factors. 👉 bit.ly/3OmMRjp

We are very excited to announce our next in-person #TPD event - join us for half a day of science and networking in Boston on September 12th! 🥳 Register here (free thanks to our sponsors): forms.gle/a8p2ALX9n2YDWt…

Very excited for our next seminar this Thursday: Derek Bartlett (formerly Pfizer Inc., now UNC-Chapel Hill) will share insights on PK-PD modelling for TPD and Kyle Mangano (Amgen 🧪🔬🧬) will present how VIPER-TACs co-opt viral E3s. 👉Join us at 12 PM EST/ 6 pm CET (back to original schedule)!

We are thrilled to have @georg_e_winter CeMM return to the DFCI TPD webinar this Thursday! Georg will talk about how inhibitors can supercharge endogenous degradation mechanisms. Very much looking forward! 👉Join us at 12 PM EST/ 6 pm CET (hybrid format)

It seems that the big migration is finally happening 🦋 And it feels just like #scienceTwitter did a few years ago! If (when...?) you join make sure to follow the #TPD starter pack: go.bsky.app/FreGFDW

📣 Please share: We’re hiring a tenure-track Group Leader in Multicellular Systems to explore the molecular and cellular mechanisms driving the formation, maintenance, or destabilization of tissues, organs and organisms. Apply at: fmi.ch/education-care…

Join us for the final TPD webinar of 2024 on 12/19. @FleurMFerguson & Eric Wang - "ZBTB11 Degraders Target Metabolic Vulnerabilities in K-Ras Inhibitor Resistant PDAC" Slava Ziegler - "Targeting IDO1 by monovalent degraders exploiting the native IDO1 degradation mechanism"

Very excited for our next seminar this Thursday (March 20th): Martin Schwalm (Structural Genomics Consortium (SGC), form. Knapp lab) will discuss UPS inhibitors and Dean Clift (TRIMTECH) will share insights on hijacking TRIM21! 👉Join us at 12 PM EST/ 5 pm CET (‼️US/EU daylight saving mismatch‼️)

📢 Save the Date! The next FREE Dana-Farber TPD In-Person Event is coming soon! Join us for an afternoon of cutting-edge science, networking, and community building focused on Targeted Protein Degradation (TPD). Stay tuned for registration and speaker details.

Tune in this Thursday for two great #TPD talks: 1) Maria Rodriguez-Rios & Conner Craigon University of Dundee Centre for Targeted Protein Degradation will discuss BromoCatch 2) Mark Mabanglo & Mahmoud Noureldin Ontario Institute for Cancer Research (OICR) will present DCAF1-PROTAC-WDR5 structures 👉Join us on May 29th at 12 PM EST/ 6 pm CET

Join us for the DFCI #TPD seminar this Thursday! We’ll hear from two outstanding speakers: 1) Kimberly Stegmaier Stegmaier Lab will discuss targeting fusion TFs 2) Leo Kiss Max Planck Institute of Biochemistry (MPIB) will share insights into the ubiquitin code Tune in 👉 bit.ly/3OmMRjp

More cyclin K degraders! Loved contributing to this study showing how binder derivatisation unlocks gain-of-function activities in the right systems. Beautiful chemistry led by Zhe Zhuang - I am a big fan of the acrylamide π-system examples: double bonds ≠ just warheads💡