Excited to share our new story about Vps13. Here we showed the PxP motifs binding mechanisms with Vps13 VAB domain and discovered two new scramblases, MCP1 and XK for Vps13 bulk lipid transfer. rupress.org/jcb/article/22…

Mitoguardin-2 is a lipid transporter and its lipid transfer ability is required for function biorxiv.org/cgi/content/sh… #bioRxiv

Excited to share the story about mitoguardin-2, which we found is a non-specific phospholipid transporter and whose ability to transfer lipids is essential for its function in mitochondria morphology and lipid droplet formation

Mitoguardin-2–mediated lipid transfer preserves mitochondrial morphology and #LipidDroplet formation, say Zhouping Hong Zhouping Hong, Karin Reinisch and colleagues Yale Cell Biology: bit.ly/3zcTxt3 #Organelles #Membrane #lipid #mitochondria #ER_literature

Mitoguardin-2's lipid transfer ability is essential for its function in #mitochondria. Zhouping Hong, Reinisch et al. Yale Cell Biology show that mitoguardin-2–mediated lipid transfer preserves mitochondrial morphology and #LipidDroplet formation bit.ly/3zcTxt3

First transatlantic preprint from the Graef Lab! We found that Atg2 cooperates with Vps13 to channel phospholipids into autophagosome membranes during #autophagy. Very proud of the work from Rahel Dabrowski and susanna.tulli! biorxiv.org/content/10.110…

Attending the #CellBio2022 for the first time. I will present my work on mitoguardin 2 with poster P2124 titled "MIGA2 is a lipid transporter and its lipid transfer ability is essential for its role in mitochondrial and lipid droplet biology" in Organelle Contact Sites session.

The Melia Lab is excited for #CellBio2022! Check out posters by our awesome grad students at the Autophagy session on Sunday (Devin Fuller B577 and Emily B578) and Establishing and Maintaining Organelle Structure on Monday (Taryn Olivas B433 and Justin Korfhage B432). (1/2)

Tomorrow at 12.15-13.45pm American Society for Cell Biology #CellBio2022 , please find me at board No. 448 for details about mitoduardin-2.😁😁😁

Got my negative COVID test results yesterday. Haven’t heard anyone catch COVID during the American Society for Cell Biology #cellbio2022 . That’s a big success already. Not to mention the great science and connections I learned and made.😆😆😆

Signal sequences encode information for protein folding in the endoplasmic reticulum, say Sha Sun, Xia Li, and Malaiyalam Mariappan Mals Mariappan @yalewestcampus Yale Cell Biology: bit.ly/3ukxOfV #ProteinHomeostasis #Biochemistry

The Mi lab at Yale School of Medicine is recruiting postdocs. Wei is on my thesis committee and super nice.

Mitochondria regulate intracellular coenzyme Q transport and ferroptotic resistance via STARD7 nature.com/articles/s4155…

Glad to defend my thesis in person!!! Thank you all in Yale Cell Biology for your help during the last five years😁😁😁

Rahel Dabrowski Rahel Dabrowski, Susanna Tulli susanna.tulli, & Martin Graef Graef Lab discover that two conserved bridge-like tether proteins, Atg2 & Vps13, drive parallel phospholipid transfer into rapidly forming autophagosomes during #autophagy bit.ly/4239NJ4

⚡️FLASH-PAINT 💡- rapid, highly efficient multiplexing (super-resolution) microscopy - is out on bioRxiv. (biorxiv.org/content/10.110…) We hope our 12-color super-resolution images electrify you as much as us: cellular complexity unlocked! Florian Schueder Yale Cell Biology #DNAPAINT🧬🔬

Let’s start the week in style: just out in Biorxiv one of the most important results from my lab, with the Reinisch lab Yale School of Medicine: “Lipid scrambling is a general feature of protein insertases”. The title pretty much sums it up. Short 🧵(1/13). biorxiv.org/content/10.110…

Nascent Chain Ubiquitination is Uncoupled from Degradation to Enable Protein Maturation biorxiv.org/content/10.110…

Congratulations to Xinbo Wang on the interesting finding of LRRK2's membrane remodeling ability!

New work from the Reinisch lab at Yale Cell Biology with the help of Melia Lab and the Burke lab: Spartin-mediated lipid transfer facilitates lipid droplet turnover