Glad to launch another collaboration with SpiroChrome! Spirochrome

Very sad news. He was a pivotal contributor to the probes community and beyond.

Nice work!

🚨Excited to share my latest postdoc work in this #biorxiv preprint on developing split-HaloTag recorders for capturing cellular transient kinase activity, Kinprola (kinase activity dependent protein labeling). biorxiv.org/content/10.110… 🧵 (1/7)

🎉🍾10 YEARS - NEW WEBSITE! 🎂 Join us in celebrating Spirochrome's 10th anniversary and visit our new website! spirochrome.com 10 years ago, the freshly founded Spirochome started commercializing its first two products, SiR-actin and SiR-tubulin! Today, with about 40

A nice talk from Stefan in PKU, with a lot of mitochondria, superresolution, and some twists to cryoEM in the end . Then we ended the day in the Emperior's diner for dinner😀 JakobsLab Zhixing Chen Peng Xi

Our Gentle Rhodamines is finally published ACS Central Science. See the healthy cytoskeleton free from photodamage even after 800 frames! 🦾💪 pubs.acs.org/doi/10.1021/ac… Great collaboration with Julian Kompa, the Johnsson group, and Spirochrome! Julian Kompa Spirochrome Tianyan Liu

😍 PKmem 555 in action! Thanks for sharing!

I'm flattered everytime I see a multi-color movie with our gentle dyes together with mStayGold!

the department of polymer at Peking University is looking for 2 PIs at both junior and mid-career levels, all backgrounds are welcomed, but would prioritize those in polymer physics, functional soft matters, and AI for polym. sci. Pls contact me ([email protected]) or RT.

Great collaborations between junior PIs😀PK mito dyes excel in applications beyond imaging and beyond traditional model animals!

How proximal is proximity labeling❓ Using DNA nanorulers we found that TurboID/BioID are largely contact labeling, while APEX2 also bears a major contact labeling pathway in parallel with diffusive labeling. biorxiv.org/content/10.110… Special thanks to Alice Ting for discussions!

Happy New Year, everyone🍀 Excited to see one of my live-cell STED super-resolution microscopy images featured in this year’s ibidi GmbH calendar! 🎉 Mitochondria stained by PKMO by Zhixing Chen and 610CP-CTX by Chromatin labeling and imaging , recorded on an Abberior Expert Line.

My heart is broken as I announce the passing of my beloved husband, science partner and friend, Michael Sheetz. A remarkable scientist we packed 40 years of living into 20. Rejuvenation of senescent cells and mice in Press in Aging Cell; his last words were this was his best work

March 27 (Thu), 9:00–11:40 Speakers: Hiroyoshi Fujioka (Inst. Sci. Tokyo), Zhixing Chen (Zhixing Chen, Peking Univ.), Satoshi Okada (Inst. Sci. Tokyo), Fan Zhang (Fudan Univ.), Hao Zhu (Hao Zhu 朱浩, Kyoto Univ.), Chu Wang (Chu Wang, Peking Univ.) pub.confit.atlas.jp/en/event/csj10…

Today we report the directed evolution of HUH (a sequence-sequence covalent protein tag for ssDNA labeling) into rHUH, a sequence-specific covalent protein tag for RNA labeling. rHUH was hard to engineer: the initial HUH template had no RNA activity, so we started with RNA-DNA

Here come our new palette of fluorescent dyes. The BD dyes endeaves to balance glowy brightness, robust photostability, and biocompatibility. Let's boost 4D dynamic super-resolution imaging!!! nature.com/articles/s4159… Spirochrome

Check it out at PNAS today. Thank you Alexandre for the collaboration!! PK Mem probes offer long time-lapse imaging of cell membrane dynamics. Made possible by Jing Ling, Yitong Liu, and all the collaborators! Available Spirochrome