ACS Central Science
@ACSCentSci
EiC @CarolynBertozzi and ACS Central Science team on #openaccess research at the interfaces of chemistry, biology, materials science, physics, & engineering
ID:2180867466
http://pubs.acs.org/centralscience 07-11-2013 21:12:49
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Site-selective labeling of the immunophilin FKBP12 using fluorogenic azo-functionalized BODIPYs allows rapid and wash-free detection of immunosuppressants Marco Bertolini DYNAFLUORS Lavilla Lab
NEW #ASAP
Read it here: go.acs.org/9bO
Minimum variance sampling analysis (MVS-A) is a fast machine-learning approach enabling the identification of both true bioactive compounds and false positives in high throughput screening data
NEW #ASAP by Sieber Lab TU München
Read it here: go.acs.org/9aF
#ICYMI
Our NEW issue is now live!
Read it here: go.acs.org/99E
Supplementary cover story by Dr Laura Sanchez & Lu Wei UC Santa Cruz Science go.acs.org/99F
“Blue Light, Camera, Action!”
NEW #FirstReactions by Olof Idevall-Hagren & Paul O’Callaghan Uppsala University discussing the recent work by Jeremy Baskin Julia Xiang-Ling Li Reika Tei Masaaki Uematsu Weill Institute for Cell & Molecular Biology CornellChemistry #lipidtime go.acs.org/99D
Read it here: go.acs.org/99C
Pyrazinone Biosynthesis and Signaling─Myxo Style
NEW #FirstReactions by Sandra Loesgen (loesgenlab.bsky.social) & Rudolf Lab discussing work by Changsheng Wu, Wei Zhang, Yue-Zhong Li & team #ShandongUniversity go.acs.org/97B
Read it here: go.acs.org/97A
Ji and co-workers develop 5-BrUrd-modified tRNA activity-based probes to study the molecular basis of dihydrouridine formation by hDUS2 and screen small molecule inhibitors KleinerLab Princeton Chemistry
NEW #ASAP
Read it here: go.acs.org/95A
Flipping the GPCR switch: CarreiraGroup Roman Sarott report generalizable structure-guided ligand modification transforming a Cannabinoid Receptor 2 agonist into an inverse-agonist
NEW #ASAP
Read it here: go.acs.org/94x
Design of cytotoxic T cell epitopes for enhancing antigen processing and presentation, enabled by machine learning of human degrons and cytosolic delivery with two anthrax proteins
NEW #ASAP by PenteluteLab RGB Lab @ MIT & team
Read it here: go.acs.org/93q
A Large Open-Source Zeolite Synthesis Dataset Enables Machine Learning Rationalization of Zeolite Structure-Synthesis Relationships
NEW #ASAP by DMSE at MIT Olivetti Group @ MIT RGB Lab @ MIT MIT ChemE Dept Román Lab @ MIT ITQ (UPV-CSIC)
Read it here: go.acs.org/92l
Thiol-mediated uptake (TMU) is an intriguing enigma in current chemistry and biology. Our new paper in ACS Central Science provides a solid basis to understand TMU, enable and prevent entry into cells along at least three orthogonal dynamic covalent networks
pubs.acs.org/doi/10.1021/ac…
Automated Flow Peptide Synthesis Enables Engineering of Proteins with Stabilized Transient Binding Pockets
NEW #ASAP by TU Darmstadt (@Hausch_lab) 's Twitter Profile">Structure based drug research TU Darmstadt & team TU Darmstadt
Read it here: go.acs.org/8U7