Very exciting to disclose the remarkable reactivity of hydrazide in nickel-catalyzed cross-coupling. The reaction conditions are very simple—only nickel, ligand, a base, and solvent. The reaction proceeds rapidly, and the TLC results are super clean. Handling this radical

Electrifying synthetic community without electrifying a radical precursor

Final version has appeared today in Science Magazine :science.org/doi/epdf/10.11…

Final version appearing today in Nature Chemistry : nature.com/articles/s4155…

Thank you, Nature Chemistry, for this New Year's gift! Delighted to see my work online today. We constructed a bicyclic platform from simple serine, achieving remarkable stereoselectivity from the convex face. Many thanks to flow electrolysis collaboration and to the entire team

Thank you for the highlight!! A simpler way to make complex piperidines cen.acs.org/synthesis/simp… via C&EN (Chemical & Engineering News)

Great extension of rAP!!!

Appearing today in Science Magazine : science.org/doi/10.1126/sc…

Holy moly!!

One device, endless possibilities. ElectraSyn combines stirring, electrolysis, and analytics—all in one compact system. Set-up some electrifying chemistry with Jiayan_He and see you at ACS San Diego soon! 💡🔬

No need to “deep fry” your molecules for Ni-catalyzed C-H activation—turns out it works at just 50 °C👀 Full story in this work

Appearing today in nature : nature.com/articles/s4158…

Small bits have gone radical!

This is how you enable uptake of a new method! Hats off to the Knight Chemicals team for making a hydrazides coupling starter kit tailor made for medicinal chemists! Obviously I’m biased since I adore Baran Lab chemistry and the folks that develop it but dang what a product.

Nice application of electrochemical decarboxylative coupling!

rAP is dropping the beat in the total synthesis😎

We are proud to present our work on something really special, appeared in ChemRxiv today. We unlocked the synthetic application of DMF distonic radical anion with electrochemistry! Interested in the full story? See below! (1/n) chemrxiv.org/engage/chemrxi…

As usual from Waldvogel’s group — an excellent review showing how redox drives non-redox reactions like condensations. Funny enough, many common dehydrating agents (SOCl₂, oxalyl chloride, even P₂O₅) are also redox products... …mistry-europe.onlinelibrary.wiley.com/doi/10.1002/cs…

Mechanism of Redox-Neutral Radical Cross Coupling (another fun collaboration with the Blackmond Group), out today in ChemRxiv : chemrxiv.org/engage/chemrxi…

Across two studies in Science Magazine and nature, Phil Baran’s lab (Baran Lab) reveals a practical radical cross-coupling platform for constructing complex molecules using sulfonyl hydrazides—cleanly releasing nitrogen like a “rocket boost” for molecular complexity. With