Anemia might be the most common lab finding I’ve seen in my first month on inpatient servide. Although frequent blood draws are the most common cause, it helps to think broadly:

1.What if we explored different models for how labs could run? For example? the multi-PI lab. Presently every PI is like a decathlete: paper writing, grant writing, project management, budgeting, mentoring, etc. It would be so fun to run lab w/ other PIs & divide these chores up!

My politics is this

Congratulations to Dr. Walter Chan (Walter Chan, MD, MPH), our Director of the Center for GI Motility & Director of Clinical Research Education, for his #promotion to Associate Professor of Medicine at Harvard Medical School Harvard Medical School 🍾 #BWHMotility #BrighamGIFaculty #BrighamGIAlum

Paper is finally out in Nature Genetics! "Cancer cell states recur across tumor types and form specific interactions with the tumor microenvironment" Check out our catalog of conserved cancer cell states defined by scRNA-Seq & ST. Congrats @BarkleyDalia! nature.com/articles/s4158…

Attempts to reinforce a leaky physician-scientist “pipeline" often turn to an institutional narrative. Here, we reflect on the application, interview, and match process as PSTP trainees. APSA Michael Rockman, MD, PhD Ben Reisman MD PhD Jamarius Waller, MD, PhD Yasmin Kamal, MD, PhD medrxiv.org/content/10.110…

Do you want to get into scRNA-seq but are lost in the sea of never-ending papers? No worries, I got you covered. Here's a list of the best review that have help me understand the core concepts of the technique, analysis and interpretation:🧵

Better title for this study might have been: “Colonoscopies prevent cancers and deaths only if people do them” Must recognize that study was more about “invitation for colonoscopy” than “effectiveness” nejm.org/doi/full/10.10…

5 websites for drawing scientific figures: 👇 🧵

Valuable #immunology cell atlas: #scRNAseq + paired B & T cell receptor seq for 330,000 tissue-resident immune cells across 16 human tissues. CellTypist: new & robust immune cells annotation algorithm, finding 101 immune cell types in 1,000,000 cells‼️ Why this is important👇🧵

Key concept for physician-scientist trainees (and programs) to embrace is that “Real Life” doesn’t wait for us to finish training, nor should it. I am an intern, father, scientist, husband, colleague, friend, neighbor, son… and I am all of these things at the same time.

📢🥁By popular demand presenting the TOP Oncology publications of 2022. PS: List not exhaustive - so feel free to tag & add important papers to the list OncoAlert NEJM The Lancet Oncology Annals of Oncology Nature Medicine nature Cancer Discovery

Out now Immunity! Our comprehensive #singlecell atlas of >720k intestinal cells from #crohnsdisease patients uncovers transcriptional heterogeneity across tissues/inflammation states & identifies potential regulators of fibrosis. bit.ly/3Jp85M0 @MGH_RI Broad Institute

In research out today in nature, the Rabinowitz Lab's “Slow TCA flux and ATP production in primary solid tumours but not metastases” quantifies for the first time a cancerous tumor’s low energy budget. Great work Josh, Dr. Caroline Bartman and all: bit.ly/3YbMr1W #cancer

Thread / The 5 sections of an effective Specific Aims Page when writing a R01. #ASC2023 #FOAmed 1/ Introduce the topic. Less numbers (everyone has stats), keep it short and pithy. Communicate the fierce urgency of NOW.

🔥Check out our new paper🔥 Make Science Disruptive Again! All graduate programs should teach the CREATIVE SCIENTIFIC PROCESS to help change the research system and increase the disruptiveness of science projects. Martin Lercher Nature Biotechnology nature.com/articles/s4158…

Spatial periodicity in grid cell firing is explained by a neural sequence code of 2D trajectories biorxiv.org/content/10.110… Thank you to Rebecca R.G. and Giorgio Ascoli for a fantastic collaboration!

The residents have unionized

Do you use logistic regression? If so, you’ll want to read the thread below. ⚠️ Warning: Memes, charts, #rstats, and practical advice ahead.