Differential recruitment of AWI/SNF complexes directs selective activation of inflammatory genes in macrophages - congrats to HargreavesLab for another cool story within a month 🎉🎉Different remodeling complex dependence between enhancer and promoter activation is fascinating!

We are excited to share our work dissecting how distinct SWI/SNF variants cooperatively reorganize the macrophage epigenome upon inflammatory signals and facilitate appropriate immune responses, now out in Immunity. authors.elsevier.com/a/1jCxE3qNrUxt…

PD-L1 in macrophages recognizes lysed yeasts by binding to ribosomal proteins and controls IL-10. congrats Kai Li, David Underhill and all nature Cedars-Sinai Academic Medicine Surprising and cool finding! A possible way to QC the effectiveness of microbial defense? nature.com/articles/s4158…

#MucosalImmunologyPower! 💥 Join this amazing lineup of world leaders in mucosal #immunology on November 4-5 Harvard Medical School Harvard University! We will select as many oral talks as possible, & we want to share ours, & hear yours, best science!! Link to register here 👉 web-eur.cvent.com/event/723ef7a2…

happening now! breastmilk antibodies program homeostatic immunity to the microbiota!

Vaccines that hyperactivate dendritic cells protect old and young mice from cancer in contrast to traditional vaccine! Great insights into the mystery of how vaccine works and huge implications. Congrats to all 👏🏼 Jonathan Kagan Xavier Lab Ivan Zanoni Charlie Evavold Pascal Devant

highly recommended!

mighty twitter (X), does some one happen to fly from Boston to Madriad on Friday? need a favor to bring a document over, bc earliest arrival date from Fedex/DHL/UPS is next monday 🙏

9am EST from Ting Zhou from westlake university, new, cool and unpublished work about dendritic cell migration with CRISPR in vivo screening!

Terrific work from Lauren Landau Jonathan Kagan identifying modular motifs for IFN activation and using synthetic biology concept to understand the rules of complex signaling integration downstream of PAMP receptors congrats to all 👏🏼🎉 Molecular Cell Boston Children's Harvard Medical School

Glad to share our review article Annual Reviews on tissue-resident innate and adaptive lymphocytes in cancer. Defining their identities and sensing mechanisms shall guide targeting such prewired and priming-dependent defense responses for cancer therapies. doi.org/10.1146/annure…

I am excited to share the results from my postdoc with Jonathan Kagan on the detailed characterization of the cell biology underlying Toll-like receptor (TLR) signaling in innate immune cells, published today in nature: nature.com/articles/s4158… Here’s a thread with our key findings 👇

What’s many may be ONE! classic diagrams of signaling pathways with proteins and arrows illustrating information passed on from one to another. That picture is changed today! ALL components form a mega intracellular signaling complex! Congrats to Jonathan Kagan Daniel Fisch

📢Super excited to announce that the Chidley lab will open Duke Pharmacology & Cancer Biology Department in September 2024, alongside the Alicia Darnell lab🥳. The Chidley lab will use genetic screening approaches to dive into the world of transporter proteins and explore how they drive the movement of nutrients,...

Evolutionary Medicine, 2nd Ed Will be out in a couple of weeks!

A good summer day celebrating new lab members and some cool science! picking some peaches and cherries, apple ciders, pizza and games ☀️🍒🍑🍕🕶️

Two rising stars everyone needs to look out for!

For all those virology post-docs, tenure-track Assistant Professor position available in the Dept of Microbial Pathogenesis at Yale. Great department and community. Please apply. Yale School of Medicine YaleMicroPath apply.interfolio.com/151755

Our newest work is finally online at Nature (rdcu.be/dSZeH), but if your looking for a more digestible bite, check out this description of our work in Popular Science by Laura Baisas! Extra thanks to Clive McKimmie (VHIT) 🦟🦠🐁 for the mosquito saliva! popsci.com/health/allergi…

💥Last day💥 for early bird registration to #MucosalImmunology2024! JOIN US: Jie Sun, Dr. Shruti Naik, Jose Ordovas-Montanes, Smita Gopinath, Megan Orzalli & Gretchen Diehl; Scott Snapper; Carolyn Coyne! Register & submit your abstract here 👉bit.ly/3RpweoY