🐙 ALERT! So when you put an octopus in cold water it recodes 13,000 codons (1/3 of all recoding sites!) via massive RNA editing in the brain!! And this apparently alters the function of synaptic proteins! 🤯🤯🤯 That’s insane (but not for the octopus) cell.com/cell/fulltext/…

The quest to grow decaf coffee. ♨️ Companies & academics are using gene-editing to remove caffeine from Arabica & Robusta trees. But there are already plenty of ways to make decaf coffee. What gives?🧵

We're so back

Here come LYMTACs - lysosomal degradation mediated by heterobifunctionals bringing a protein of interest together with lysosomal membrane proteins. Currently relies on fusion proteins due to lack of ligands for said membrane proteins, but cool anyway. 😎 biorxiv.org/content/10.110…

Just had a call from the Royal Swedish Academy of Science begging me not to release the tweet thread about how the Nobel Prizes are actually about North English Industrial Strategy.

Great bit of Northern industrial history her - how the Industrial Revolution led to the recent Novel prize for Chemistry.

The future has landed

Excited to be Festival of Biologics representing Patsnap . A lot of excitment around AI and insilico models for biologics design!

I’m no patent attorney but surely such claims are too broad to be valid?!

Watch BioSpace below for why patents data holds the key to unlocking AI drug discovery biospace.com/webinar-revolu…

Never mind the UK budget, PatSnap's new AI can identify inventions and automatically screen for patents and literature. Great piece @fastcompany! fastcompany.com/91217588/patsn…

0.1% Growth. We shouldn't accept this. Today, we're releasing the LFG Bill. The Bill by-passes the blockers in planning and fast-tracks the building of Nuclear Power Stations, Overhead Cables and Data Centres. Join LFG and help us make growth legal again🧵👇

Great Overview from the team of 60 small molecule drugs first global approvals in 2024! Key takeaways:- 1. Although FDA remains the most popular first apporval destination, China is closing the gap with 21 approvals - testament to a faster clinical and regulatory environement?

Britain is in fast decline. Talent is fleeing. Infrastructure is crumbling. Wages have stagnated. Cost of living has skyrocketed. We need AMBITIOUS and BOLD changes NOW. It is a GOOD THING that this govt. has made an effort in their new infrastructure bill However...

When you come back from paternity leave and they’ve replaced the entire SaaS suite with agentic AI