Welcome to Asimov Press, a new publishing venture that features writing about biology. Our magazine and books will cover a broad range of topics, including biosecurity, vaccine development, and the long arc of progress in genetic engineering. Learn more: press.asimov.com/resources/welc…

What if we could inducibly create thousands of structural variants and ecDNAs in human cells and see which ones survive? biorxiv.org/content/10.110… I’m excited to share our story on scrambling the human genome by combining prime editing, repetitive elements, and recombinases. A🧵

🌱📡 We've engineered bacteria to 'talk' to plants for programmable microbe-to-plant communication, opening new doors for sustainable agriculture: doi.org/10.1038/s41467… Nature Communications

We're hiring! We're taking another big leap in using synthetic biology to engineer materials - this time for sustainable food and textiles. In the next few weeks, we've up to 4 postdoc positions opening up. I'd love to hear from anyone interested in joining us this year. Pls RT🔁

New preprint from our lab is up on bioRxiv - a really awesome synthetic genomics paper that Xinyu Lu from the team has been brewing for the last few years. @Xinyu80256297 biorxiv.org/content/10.110…

Check out the movie that summarises our papers out now in Molecular Cell youtube.com/watch?v=atLspl…🧬🎞️

Arjun Raj Mark Budde (hiring wetlab, DMs open) 🦕🏆 Uri Alon In case it's helpful to anyone, I posted the evolving set of talk tips that I share with my lab on our website. Scroll to bottom of this page: elowitz.caltech.edu/teaching. (It was once "10 commandments" but has since expanded to 25...the slide titles are currently number 5)

What if we could universally recombine, insert, delete, or invert any two pieces of DNA? In back-to-back nature papers, we report the discovery of bridge RNAs and 3 atomic structures of the first natural RNA-guided recombinase - a new mechanism for programmable genome design

Excited to share our latest research on "Engineered Yeast Multicellularity via Synthetic Cell-Cell Adhesion & Direct-Contact Signalling" posted on @bioRxiv #synbio recently! 🧵🔗[DOI](doi.org/10.1101/2024.0…)

Job alert: 2 postdoc positions available in my group Earlham Institute. Synthetic biology to 1) decode and engineer root architecture, 2) engineer plant-beneficial rhizobacteria. Reach out and please share! earlham.ac.uk/scientific-gro… 1) jobs.earlham.ac.uk/Details.asp?va… 2) jobs.earlham.ac.uk/Details.asp?va…

Our paper: "A history-dependent integrase recorder of plant gene expression with single-cell resolution" is published in Nature Communications . Congrats Cassandra Maranas for completing this work! Earlham Institute UW Biology To read the paper: rdcu.be/dYxtF nature.com/articles/s4146…

Genome engineering excelled at small nucleotide changes, but large edits remained challenging. Recent innovations are changing this. We reviewed the field of structural variant engineering Nature Genetics 🧬 Juliane Weller Thomas Vanderstichele @LeopoldParts nature.com/articles/s4158…

Come and join us at a free complementary Japan-UK Engineering Biology meeting after the main ESSL conference (essl2025.org). A few spaces left to some see some of the up and coming superstars of #synbio in the UK!